Study on the variation of visual evoked potential and its diagnostic value in children with optic neuritis

中国小儿急救医学 Pub Date : 2019-11-20 DOI:10.3760/CMA.J.ISSN.1673-4912.2019.11.008

Jingyong Sun, Xin Wang, Wenmin Yang, Xiaoyue Wang

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引用次数: 1

Abstract

Objective To investigate the characteristics and clinical value of visual evoked potentials(VEP) in children with optic neuritis. Methods The VEP of 33 children with optic neuritis were tested by NICOLET evoked potential instrument.The results were compared with those of cranial and/or orbital MRI and fundus examination, and the consistency with visual performance was analyzed.The correlation between visual sensitivity and VEP results was analyzed. Results Among 33 children with optic neuritis, the abnormal rate of VEP in 52 abnormal eyes was 88.5%; the abnormal rate of cranial and/or orbital MRI was 38.5%; the abnormal rate of fundus examination was 62.2%; the abnormal rate of VEP examination was significantly higher than that of cranial and/or orbital MRI and fundus examination (P<0.05); the consistency rate between VEP examination and visual acuity was 84.8%.The consistency rate between pattern reversal visual evoked potential (P-VEP) and visual acuity was 86.8%, and that between flash visual evoked potential (F-VEP) and visual acuity was 82.1%.With the increase of visual impairment, the percentage of P100 wave loss increased gradually.There was no correlation between visual acuity and the prolongation of P100 wave latency. Conclusion There are significant differences between VEP and fundus examination and MRI, the sensitivity of VEP is superior to both.P-VEP is more consistent with visual acuity than F-VEP.VEP has certain value in evaluating the degree of visual impairment in children with optic neuritis.It can not be used to evaluate the level of optic sensitivity when the latency of P100 wave is prolonging. Key words: Optic neuritis; Visual evoked potentials; Visual; Children

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视神经炎患儿视觉诱发电位变化及其诊断价值的研究

目的探讨儿童视神经炎视觉诱发电位（VEP）的特点及临床价值。方法应用NICOLET诱发电位仪对33例视神经炎患儿的VEP进行检测。将结果与颅骨和/或眼眶MRI和眼底检查的结果进行比较，并分析其与视觉表现的一致性。分析视觉敏感性与VEP结果之间的相关性。结果33例视神经炎患儿中，52眼VEP异常率为88.5%；颅内和/或眼眶MRI异常率为38.5%；眼底检查异常率为62.2%；VEP检查异常率明显高于头颅和/或眼眶MRI及眼底检查（P＜0.05）；VEP检查与视力的符合率为84.8%，模式反转视觉诱发电位（P-VEP）与视力的一致率为86.8%，闪光视觉诱发电位和视力的一致性为82.1%。P100波潜伏期延长与视力无相关性。结论VEP与眼底检查及MRI有显著性差异，VEP的敏感性优于两者。P-VEP比F-VEP更符合视力。VEP对评估儿童视神经炎的视力损害程度有一定价值。当P100波潜伏期延长时，它不能用于评估光敏感性水平。关键词：视神经炎；视觉诱发电位；视觉；儿童

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来源期刊

中国小儿急救医学

自引率

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发文量

6226

期刊介绍： Chinese Journal of Neurology was established in 1955, the predecessor of which is Chinese Journal of Neurology and Psychiatry. Chinese Journal of Neurology and Psychiatry has been indexed by MEDLINE until 1996, when it was divided into two journals, Chinese Journal of Neurology, and Chinese Journal of Psychiatry. Chinese Journal of Neurology is now indexed by EM, SCOPUS, AJ, WPRIM, CNKI, Wanfang Data, CSCD, etc. The impact factor of the journal is 2.755 in 2017, ranking the first among all neurological and psychological journals in China and among all the 142 medical journals published by the Chinese Medical Association. The journal is available both in print and online.