Circular RNA: the rings of power over cell

Q4 Biochemistry, Genetics and Molecular Biology

Biopolymers and Cell Pub Date : 2020-06-30 DOI:10.7124/bc.000a23

V. Gordiyuk, O. Mankovska

引用次数: 0

Abstract

Circular RNAs (circ RNAs) are endogenous covalently closed single-stranded noncoding RNAs (ncRNAs) without the 5′-cap and 3′-poly(A) tail derived from alternative mRNA splicing. СircRNAs are expressed across all branches of evolutionary tree, including viruses and prokaryotes, and are evolutionary conserved. CircRNAs have a constitutive al biological role. In this review, we summarized the latest data on circRNAs and highlighted their most important and studied functions in different biological processes. The generation of tricRNA.

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环状核糖核酸：细胞的能量环

环状RNA（circ-RNA）是一种内源性共价封闭的单链非编码RNA（ncRNA），无5′-帽和3′-聚（A）尾，来源于选择性信使核糖核酸剪接。СircRNA在进化树的所有分支中都有表达，包括病毒和原核生物，并且是进化保守的。CircRNA具有组成性的生物学作用。在这篇综述中，我们总结了circRNAs的最新数据，并强调了它们在不同生物过程中最重要和研究的功能。tricRNA的产生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biopolymers and Cell Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

1.10

自引率

0.00%

发文量

期刊介绍： “Biopolymer and cell” is published since 1985 at the Institute of Molecular Biology and Genetics NAS of Ukraine under the supervision of the National Academy of Sciences of Ukraine. Our journal covers a wide scope of problems related to molecular biology and genetics including structural and functional genomics, transcriptomics, proteomics, bioinformatics, biomedicine, molecular enzymology, molecular virology and immunology, theoretical bases of biotechnology, physics and physical chemistry of proteins and nucleic acids and bioorganic chemistry.