Confirmed SARS-CoV-2 infection and mortality: Associated factors in hospitalized people 75 and older

IF 1 Q3 MEDICINE, GENERAL & INTERNAL

Electronic Journal of General Medicine Pub Date : 2023-05-01 DOI:10.29333/ejgm/13042

S. A. Aruachan-Torres, D. Chavarro-Carvajal, Carlos José Ariza-Galindo, Ronald Camilo Gómez Arteaga, Sandra Milena Caicedo-Correa, Carlos Alberto Cano Gutierrez

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Abstract

Introduction: COVID-19 infection in the elderly posed challenges in health systems and clinical care by health personnel. Objective: To describe the factors associated with mortality in persons aged 75 and older with COVID-19 in a high complexity hospital in Bogotá, Colombia. Methods: Observational, analytical and retrospective study, including 509 patients aged 75 and older hospitalized with COVID-19. Results: 40.47% died during hospital stay. It was found that a shorter time of symptom onset at admission, a respiratory rate greater than 20 breaths per minute, having thrombocytopenia, elevated lactate dehydrogenase and elevated D-dimer were associated with higher in-hospital mortality. Conclusions: There is an association between mortality and the presence of dyspnea, fever and delirium. Paraclinical results with lactate dehydrogenase >350 (U/L), the presence of elevated D-dimer greater than 1,000 μg/L, as well as a Pa02/Fi02 ratio with a median of less than 90, were associated with higher mortality.

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确诊的严重急性呼吸系统综合征冠状病毒2型感染和死亡率：75岁及以上住院患者的相关因素

简介：老年人新冠肺炎感染对卫生系统和卫生人员的临床护理提出了挑战。目的：描述哥伦比亚波哥大一家高度复杂医院75岁及以上新冠肺炎患者死亡率的相关因素。方法：采用观察、分析和回顾性研究方法，对509例75岁及以上新冠肺炎住院患者进行研究。结果：40.47%的患者在住院期间死亡。研究发现，入院时症状发作时间较短、呼吸频率大于每分钟20次、血小板减少症、乳酸脱氢酶升高和D-二聚体升高与住院死亡率较高有关。结论：死亡率与呼吸困难、发烧和谵妄的存在有关。乳酸脱氢酶>350（U/L）、D-二聚体升高大于1000μg/L以及Pa02/Fi02比值中位数小于90的副临床结果与较高的死亡率相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Electronic Journal of General Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

3.60

自引率

4.80%

发文量