Non-Pharmacological Interventions For The Appetite And Eating Disorders In Patients With Dementia: A Cross-Over RCT

Dimitriou Tatiana-Danai, Papatriantafyllou John, Konsta Anastasia, K. Dimitrios, A. Loukas, Ioannidis Panagiotis, Koutsouraki Efrosini, Tegos Thomas, Sofia Loukou, T. Magda
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Abstract

Objectives: The most common appetite/ eating problems in patients with dementia (PWD) are loss or increase of appetite, loss or gain of weight, changes in eating behaviour, changes in the preferences of the food, developing specific eating behaviours, eating in an appropriate way or eating non-food items, and frequently demanding food or drinks, because they forget that they have eaten. Appetite/ eating disorder is an essential and common behavioral and psychological symptom of dementia (BPSD) that leads to poor quality of life, institutionalization, and affects the physiological function of many systems of the patient. Methods/ Design: 60 patients with dementia and appetite problems and their caregivers were included. The participants were suffering from all different types and stages of dementia. The study is a cross-over randomized controlled trial. The measurements used were: Mini Mental State Examination (MMSE), Addenbrooke’s Cognitive Examination Revised (ACE-R), Geriatric Scale of Depression (GDS), Functional Rating Scale for Symptoms in Dementia (FRSSD), and Neuropsychiatric Inventory (NPI). The three non-pharmacological interventions that were used: Physical Activity (PA), Music Therapy (MT), and Psycho-Educational Programme for the Caregivers (PEPC). Results: The most effective combination for the reduction of appetite problems was found in group 6: PEPC (structure routine in the hours that the food is served) (p=0.004), followed by MT (p=0.027), followed by PA (p=0.036). The same combination was the most effective for the reduction of caregivers’ burden, as well. Conclusions: There is a combination of non-pharmacological interventions (PEPC+MT+PA) that can effectively reduce the appetite/eating problems in PwD. The same combination is the most effective in reducing the caregivers’ burden, as well.
痴呆患者食欲和饮食障碍的非药物干预:随机对照试验
目的:痴呆症(PWD)患者最常见的食欲/饮食问题是食欲下降或增加、体重减轻或增加、饮食行为的变化、食物偏好的变化、发展特定的饮食行为、以适当的方式进食或食用非食物项目,以及因忘记进食而经常索要食物或饮料。食欲/进食障碍是痴呆症(BPSD)的一种重要而常见的行为和心理症状,会导致生活质量差、住院治疗,并影响患者许多系统的生理功能。方法/设计:纳入60名患有痴呆和食欲问题的患者及其护理人员。参与者患有各种不同类型和阶段的痴呆症。这项研究是一项交叉随机对照试验。使用的测量方法有:简易精神状态检查(MMSE)、阿登布鲁克认知检查修订版(ACE-R)、老年抑郁量表(GDS)、痴呆症状功能评定量表(FRSSD)和神经精神量表(NPI)。使用的三种非药物干预措施:体育活动(PA)、音乐治疗(MT)和护理人员心理教育计划(PEPC)。结果:在第6组中,减少食欲问题的最有效组合是:PEPC(食物供应时间的结构常规)(p=0.004),其次是MT(p=0.027),其次为PA(p=0.036)。同样的组合对减轻照顾者的负担也是最有效的。结论:非药物干预(PEPC+MT+PA)可有效减少PwD患者的食欲/饮食问题。同样的组合在减轻照顾者负担方面也是最有效的。
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