Post-processing methodology for the multimodal study of the left atrium during atrial fibrillation

IF 18 Q4 Medicine
T. Raoult
{"title":"Post-processing methodology for the multimodal study of the left atrium during atrial fibrillation","authors":"T. Raoult","doi":"10.1016/j.acvdsp.2023.04.043","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>In the context of a prospective study for the multimodal characterization of the left atrium<span><span> in patients undergoing </span>atrial fibrillation ablation, we developed a systematic pipeline to allow the co-registration and analysis of three different imaging modalities: LGE-CMR, 3D catheter-based invasive voltage maps and FDG uptake measured by PET.</span></p></div><div><h3>Method</h3><p>The software SLICER3D was choosed as the primary building block. As a free, open source software, it allows for the quick building and deployment of custom solutions thanks to its python wrapper. Several software solutions were developped in python using both the SLICER3D innate capabilities and the Vizualisation toolkit library (VTK) powerful post-processing power.</p></div><div><h3>Results</h3><p>Building on a previous work from Hohmann S. we developed a program allowing the importation in SLICER3D of CARTOv7 (biosense) voltage maps. Using built-in tools, 3D meshes were created from LGE-CMR and PET studies. Unto those 3D meshes, a custom program calculated a maximum intensity projection of the atrial wall along normal vectors, allowing for the creation of LGE and SUV 3D maps. Lastly, iterative point cloud registration permitted the fusion of all 3 mappings. Point-by-point test of association between low voltage, low FDG uptake and high-LGE was used.</p></div><div><h3>Conclusion</h3><p><span>We were able to fusion and do a point-by-point analysis of three different imaging studies of the left atrium in atria fibrillation: voltage maps, LGE-CMR, and PET. Software solutions developed for this post-processing pipeline are generic and could be adapted for other multimodalities studies. A prospective study using this methodology and involving patients in AF undergoing ablation is underway and will be presented at the ESC congress 2023 (</span><span>Fig. 1</span>).</p></div>","PeriodicalId":8140,"journal":{"name":"Archives of Cardiovascular Diseases Supplements","volume":null,"pages":null},"PeriodicalIF":18.0000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Cardiovascular Diseases Supplements","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1878648023001829","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction

In the context of a prospective study for the multimodal characterization of the left atrium in patients undergoing atrial fibrillation ablation, we developed a systematic pipeline to allow the co-registration and analysis of three different imaging modalities: LGE-CMR, 3D catheter-based invasive voltage maps and FDG uptake measured by PET.

Method

The software SLICER3D was choosed as the primary building block. As a free, open source software, it allows for the quick building and deployment of custom solutions thanks to its python wrapper. Several software solutions were developped in python using both the SLICER3D innate capabilities and the Vizualisation toolkit library (VTK) powerful post-processing power.

Results

Building on a previous work from Hohmann S. we developed a program allowing the importation in SLICER3D of CARTOv7 (biosense) voltage maps. Using built-in tools, 3D meshes were created from LGE-CMR and PET studies. Unto those 3D meshes, a custom program calculated a maximum intensity projection of the atrial wall along normal vectors, allowing for the creation of LGE and SUV 3D maps. Lastly, iterative point cloud registration permitted the fusion of all 3 mappings. Point-by-point test of association between low voltage, low FDG uptake and high-LGE was used.

Conclusion

We were able to fusion and do a point-by-point analysis of three different imaging studies of the left atrium in atria fibrillation: voltage maps, LGE-CMR, and PET. Software solutions developed for this post-processing pipeline are generic and could be adapted for other multimodalities studies. A prospective study using this methodology and involving patients in AF undergoing ablation is underway and will be presented at the ESC congress 2023 (Fig. 1).

心房颤动期间左心房多模式研究的后处理方法
在一项对房颤消融患者左心房多模态特征的前瞻性研究的背景下,我们开发了一个系统的管道,允许三种不同的成像模式的共同注册和分析:LGE-CMR,基于3D导管的侵入性电压图和PET测量的FDG摄取。方法选择SLICER3D软件作为主要构建模块。作为一个免费的开源软件,由于它的python包装器,它允许快速构建和部署自定义解决方案。使用SLICER3D固有功能和可视化工具包库(VTK)强大的后处理能力,在python中开发了几个软件解决方案。基于Hohmann S.先前的工作,我们开发了一个程序,允许在SLICER3D中输入CARTOv7(生物传感)电压图。使用内置工具,根据大磁共振成像和PET研究创建3D网格。对于这些3D网格,定制程序计算心房壁沿法向量的最大强度投影,允许创建LGE和SUV 3D地图。最后,迭代点云配准实现了3种映射的融合。采用逐点检验低电压、低FDG摄取与高lge之间的关系。结论:我们能够融合并逐点分析三种不同的左心房颤动成像研究:电压图、LGE-CMR和PET。为这种后处理管道开发的软件解决方案是通用的,可以适用于其他多模式研究。一项使用该方法并涉及房颤消融患者的前瞻性研究正在进行中,并将在2023年ESC大会上发表(图1)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Archives of Cardiovascular Diseases Supplements
Archives of Cardiovascular Diseases Supplements CARDIAC & CARDIOVASCULAR SYSTEMS-
自引率
0.00%
发文量
508
期刊介绍: Archives of Cardiovascular Diseases Supplements is the official journal of the French Society of Cardiology. The journal publishes original peer-reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches, review articles, editorials, and Images in cardiovascular medicine. The topics covered include coronary artery and valve diseases, interventional and pediatric cardiology, cardiovascular surgery, cardiomyopathy and heart failure, arrhythmias and stimulation, cardiovascular imaging, vascular medicine and hypertension, epidemiology and risk factors, and large multicenter studies. Additionally, Archives of Cardiovascular Diseases also publishes abstracts of papers presented at the annual sessions of the Journées Européennes de la Société Française de Cardiologie and the guidelines edited by the French Society of Cardiology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信