Characterization of Mixed Urinary Stone Compositions with Dual-Source Dual-Energy Computed Tomography in Vivo Compared to Infrared Spectroscopy

IF 0.2 4区医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Iranian Journal of Radiology Pub Date : 2021-07-31 DOI:10.5812/iranjradiol.114717

Xianghu Meng, Xue-Ying Sun, Rong Cong, L. Qi, Zengjun Wang, Ri-jin Song

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引用次数: 0

Abstract

Background: Most previous studies have demonstrated the possibility of using dual-source dual-energy computed tomography (DSDECT) to distinguish pure stones with high accuracy. While stones are usually composed of a mixture of substances, very few studies have focused on these stone compositions. Objectives: To retrospectively evaluate the diagnostic accuracy of DSDECT in predicting the composition of mixed urinary calculi in vivo compared to the postoperative infrared spectroscopy (IRS) for stone analysis. Materials and Methods: We retrospectively included 111 patients with 117 mixed urinary stones, detected by IRS, who underwent DSDECT between June 2018 and March 2020. Patients diagnosed with urolithiasis were examined by DSDECT preoperatively. The final stone composition was detected by IRS in vitro postoperatively. Also, the stone composition predicted by DSDECT was compared to the IRS results, known as the reference standard. Results: According to the results of IRS, 117 mixed urinary calculi, composed of a main constituent and minor admixtures, were divided into four groups: calcium oxalate (CaOx)-hydroxyapatite (HA) (n = 70); HA-CaOx (n = 36); uric acid (UA)-CaOx (n = 8); and cystine (CYS)-HA (n = 3). The accuracy of DSDECT in predicting different components of mixed urinary stones was 68.4%, 64.1%, 97.4%, and 97.5% for the CaOx-HA, HA-CaOx, UA-CaOx, and CYS-HA stones, respectively. The imaging characteristics of different mixed urinary stones, as shown by DSDECT, revealed that the CaOx-HA ratio value was lower than that of HA-CaOx (1.59 ± 0.11 vs. 1.66 ± 0.22; P < 0.05). Meanwhile, the computed tomography (CT) values of CaOx-HA under 150 kV were higher than those of HA-CaOx (915.41 ± 226.84 vs .799.56 ± 252.01; P < 0.05). Conclusion: Although DSDECT has a relatively low accuracy for predicting the components of CaOx-HA and HA-CaOx in vivo, its combination with the measured ratio and CT values may help differentiate these stones.

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体内双源双能计算机断层扫描与红外光谱法对混合尿路结石成分的表征

背景：以前的大多数研究都证明了使用双源双能计算机断层扫描（DSDECT）来高精度区分纯结石的可能性。虽然石头通常由多种物质的混合物组成，但很少有研究关注这些石头的成分。目的：回顾性评价DSDECT在预测体内混合性尿路结石成分方面的诊断准确性，并与术后红外光谱（IRS）进行结石分析进行比较。材料和方法：我们回顾性纳入了111名患者，其中117例混合性尿路结石，由IRS检测，他们在2018年6月至2020年3月期间接受了DSDECT。术前对诊断为尿石症的患者进行DSDECT检查。术后通过体外IRS检测最终结石成分。此外，还将DSDECT预测的石材成分与IRS结果（即参考标准）进行了比较。结果：根据IRS结果，将117例混合型尿路结石分为四组：草酸钙（CaOx）-羟基磷灰石（HA）（n=70）；HA-CaOx（n=36）；尿酸（UA）-CaOx（n=8）；和胱氨酸（CYS）-HA（n=3）。对于CaOx-HA、HA-CaOx、UA CaOx和CYS-HA结石，DSDECT预测混合性尿路结石不同成分的准确率分别为68.4%、64.1%、97.4%和97.5%。DSDECT对不同混合性尿路结石的影像学特征显示，CaOx-HA比值低于HA-CaOx（1.59±0.11vs.1.66±0.22；P<0.05），CaOx-HA在150kV下的CT值高于HA-CaOx（915.41±226.84 vs 799.56±252.01；P<0.05）。

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来源期刊

Iranian Journal of Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

0.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Iranian Journal of Radiology is the official journal of Tehran University of Medical Sciences and the Iranian Society of Radiology. It is a scientific forum dedicated primarily to the topics relevant to radiology and allied sciences of the developing countries, which have been neglected or have received little attention in the Western medical literature. This journal particularly welcomes manuscripts which deal with radiology and imaging from geographic regions wherein problems regarding economic, social, ethnic and cultural parameters affecting prevalence and course of the illness are taken into consideration. The Iranian Journal of Radiology has been launched in order to interchange information in the field of radiology and other related scientific spheres. In accordance with the objective of developing the scientific ability of the radiological population and other related scientific fields, this journal publishes research articles, evidence-based review articles, and case reports focused on regional tropics. Iranian Journal of Radiology operates in agreement with the below principles in compliance with continuous quality improvement: 1-Increasing the satisfaction of the readers, authors, staff, and co-workers. 2-Improving the scientific content and appearance of the journal. 3-Advancing the scientific validity of the journal both nationally and internationally. Such basics are accomplished only by aggregative effort and reciprocity of the radiological population and related sciences, authorities, and staff of the journal.