Electrochemical Detection of Nevirapine Using Banana Peel Extract Functionalised Nickel Selenide Quantum Dots

IF 2.7 4区化学 Q3 CHEMISTRY, PHYSICAL

Electrocatalysis Pub Date : 2022-12-24 DOI:10.1007/s12678-022-00805-8

Ginny S. Tito, Alex T. Kuvarega, Bhekie B. Mamba, Usisipho Feleni

{"title":"Electrochemical Detection of Nevirapine Using Banana Peel Extract Functionalised Nickel Selenide Quantum Dots","authors":"Ginny S. Tito, Alex T. Kuvarega, Bhekie B. Mamba, Usisipho Feleni","doi":"10.1007/s12678-022-00805-8","DOIUrl":null,"url":null,"abstract":"<div>Nickel selenide quantum dots (NiSe2QDs) were synthesised using the aqueous colloidal method with banana peel extract (BPE) utilised as a capping agent. A gold electrode modified with the BPE-capped NiSe2QDs was used for the determination of nevirapine. Characterisation of the BPE-NiSe2QDs was conducted using high-resolution scanning electron microscopy (HRSEM), high-resolution transmission microscopy (HRTEM) and small-angle X-ray scattering (SAXS) which all revealed the spherical morphology of the QDs and their small sizes (˂ 10 nm). Optical properties of the BPE-NiSe2QDs studied by ultraviolet–visible spectroscopy (UV–Vis) revealed an absorbance band at 329 nm corresponding to an energy bandgap value of 2.99 eV. The electrochemical experiments were performed using differential pulse voltammetry. The Au/BPE-NiSe2QDs/Nafion-based electrochemical sensor showed a distinctive anodic response towards nevirapine at 0.76 V. The results obtained showed that the oxidation peak current increased linearly as the nevirapine concentrations increased in the range 0–1.21 pM (0–0.322 ng/L) with a low limit of detection (LOD) of 0.024 pM (0.0064 ng/L) and sensitivity of 5.52 µA/pM. These exceptional properties are comparable to or even better than already reported sensors for complex matrices. The electrochemical sensor demonstrated high repeatability and stability. The proposed sensor was successfully used for nevirapine detection in spiked wastewater samples with satisfactory results.\n</div>","PeriodicalId":535,"journal":{"name":"Electrocatalysis","volume":"14 3","pages":"393 - 405"},"PeriodicalIF":2.7000,"publicationDate":"2022-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Electrocatalysis","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s12678-022-00805-8","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}

引用次数: 2

Abstract

Nickel selenide quantum dots (NiSe₂QDs) were synthesised using the aqueous colloidal method with banana peel extract (BPE) utilised as a capping agent. A gold electrode modified with the BPE-capped NiSe₂QDs was used for the determination of nevirapine. Characterisation of the BPE-NiSe₂QDs was conducted using high-resolution scanning electron microscopy (HRSEM), high-resolution transmission microscopy (HRTEM) and small-angle X-ray scattering (SAXS) which all revealed the spherical morphology of the QDs and their small sizes (˂ 10 nm). Optical properties of the BPE-NiSe₂QDs studied by ultraviolet–visible spectroscopy (UV–Vis) revealed an absorbance band at 329 nm corresponding to an energy bandgap value of 2.99 eV. The electrochemical experiments were performed using differential pulse voltammetry. The Au/BPE-NiSe₂QDs/Nafion-based electrochemical sensor showed a distinctive anodic response towards nevirapine at 0.76 V. The results obtained showed that the oxidation peak current increased linearly as the nevirapine concentrations increased in the range 0–1.21 pM (0–0.322 ng/L) with a low limit of detection (LOD) of 0.024 pM (0.0064 ng/L) and sensitivity of 5.52 µA/pM. These exceptional properties are comparable to or even better than already reported sensors for complex matrices. The electrochemical sensor demonstrated high repeatability and stability. The proposed sensor was successfully used for nevirapine detection in spiked wastewater samples with satisfactory results.

Abstract Image

查看原文本刊更多论文

香蕉皮提取物功能化硒化镍量子点电化学检测奈韦拉平

以香蕉皮提取物(BPE)为封盖剂，采用水溶胶法制备硒化镍量子点(NiSe2QDs)。用bpe包封的NiSe2QDs修饰金电极测定奈韦拉平。利用高分辨率扫描电镜(HRSEM)、高分辨率透射电镜(HRTEM)和小角度x射线散射(SAXS)对BPE-NiSe2QDs进行了表征，结果表明，BPE-NiSe2QDs的形貌为球形，尺寸小于10 nm。利用紫外可见光谱(UV-Vis)研究了BPE-NiSe2QDs的光学性质，发现其在329 nm处有一个吸收带，对应的能带值为2.99 eV。电化学实验采用差分脉冲伏安法进行。Au/BPE-NiSe2QDs/ nafion电化学传感器对0.76 V的奈韦拉平有明显的阳极响应。结果表明，在0 ~ 1.21 pM (0 ~ 0.322 ng/L)范围内，氧化峰电流随奈韦拉平浓度的增加呈线性增加，低检出限(LOD)为0.024 pM (0.0064 ng/L)，灵敏度为5.52µa /pM。这些特殊的性质与已经报道的用于复杂矩阵的传感器相当，甚至更好。该电化学传感器具有较高的重复性和稳定性。该传感器成功地用于加标废水样品中奈韦拉平的检测，结果令人满意。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Electrocatalysis CHEMISTRY, PHYSICAL-ELECTROCHEMISTRY

CiteScore

4.80

自引率

6.50%

发文量

审稿时长

>12 weeks

期刊介绍： Electrocatalysis is cross-disciplinary in nature, and attracts the interest of chemists, physicists, biochemists, surface and materials scientists, and engineers. Electrocatalysis provides the unique international forum solely dedicated to the exchange of novel ideas in electrocatalysis for academic, government, and industrial researchers. Quick publication of new results, concepts, and inventions made involving Electrocatalysis stimulates scientific discoveries and breakthroughs, promotes the scientific and engineering concepts that are critical to the development of novel electrochemical technologies. Electrocatalysis publishes original submissions in the form of letters, research papers, review articles, book reviews, and educational papers. Letters are preliminary reports that communicate new and important findings. Regular research papers are complete reports of new results, and their analysis and discussion. Review articles critically and constructively examine development in areas of electrocatalysis that are of broad interest and importance. Educational papers discuss important concepts whose understanding is vital to advances in theoretical and experimental aspects of electrochemical reactions.