Functional interplay between the Hippo pathway and heavy metals

IF 2.6 Q3 ONCOLOGY

Molecular and Cellular Oncology Pub Date : 2022-04-09 DOI:10.1080/23723556.2022.2061297

Han Han, Alisa L. Mahieu, Lucas de Paula, Wenqi Wang

引用次数: 0

Abstract

ABSTRACT Emerging studies highlight the Hippo pathway as an important player in organ size control, tissue homeostasis, regeneration, development, and diseases, but our understanding of its roles and regulations remains incomplete. Our recent work reported a functional interplay between the Hippo pathway and heavy metals, providing new insights into this key signaling pathway.

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Hippo通路与重金属之间的功能相互作用

摘要：新兴的研究强调，Hippo通路在器官大小控制、组织稳态、再生、发育和疾病中发挥着重要作用，但我们对其作用和调节的理解仍然不完整。我们最近的工作报道了Hippo通路和重金属之间的功能相互作用，为这一关键信号通路提供了新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular and Cellular Oncology Biochemistry, Genetics and Molecular Biology-Cancer Research

CiteScore

3.20

自引率

0.00%

发文量

期刊介绍： For a long time, solid neoplasms have been viewed as relatively homogeneous entities composed for the most part of malignant cells. It is now clear that tumors are highly heterogeneous structures that evolve in the context of intimate interactions between cancer cells and endothelial, stromal as well as immune cells. During the past few years, experimental and clinical oncologists have witnessed several conceptual transitions of this type. Molecular and Cellular Oncology (MCO) emerges within this conceptual framework as a high-profile forum for the publication of fundamental, translational and clinical research on cancer. The scope of MCO is broad. Submissions dealing with all aspects of oncogenesis, tumor progression and response to therapy will be welcome, irrespective of whether they focus on solid or hematological neoplasms. MCO has gathered leading scientists with expertise in multiple areas of cancer research and other fields of investigation to constitute a large, interdisciplinary, Editorial Board that will ensure the quality of articles accepted for publication. MCO will publish Original Research Articles, Brief Reports, Reviews, Short Reviews, Commentaries, Author Views (auto-commentaries) and Meeting Reports dealing with all aspects of cancer research.