Effect of Tratak (Yogic Ocular Exercises) on Intraocular Pressure in Glaucoma: An RCT

IF 1.1 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE
Sankalp, T. Dada, R. Yadav, H. Sharma, R. Netam, K. Kochhar
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引用次数: 5

Abstract

Introduction: In healthy subjects, the intraocular pressure (IOP) is maintained by a dynamic equilibrium between continuous production of aqueous humor by ciliary bodies and continuous outflow through the two drainage pathways: trabecular meshwork and uveoscleral outflow. Here, we hypothesized that yogic ocular exercises, including extraocular muscles exercise, and modified Tratak Kriya (mTK), might reduce the IOP as well as stress and improve quality of life (QoL) in patients with glaucoma. Methodology: A parallel two-arm randomized controlled trial (RCT) was conducted in glaucoma patients (Control group and Intervention group). Control group patients were on standard medical treatment and intervention group patients practiced a Yoga-based lifestyle intervention (YBLI) for 4 weeks as add-on therapy with their standard medical treatment. All Participants were assessed at baseline day 1, day 14 (D14), and day 28 (D28). A minimum of 30 patients were recruited in each group. Results: We did not observe any statistically significant different mean IOP of right (IOP-r) or, left eyes at any time point as well as cortisol level and QoL between the two groups. However, with in intervention group, there was a reduction in IOP-r at D14 (15.54 ± 2.81 mmHg) and D28 (15.24 ± 3.1 mmHg), P = 0.006 and 0.001, respectively, compared to their baseline IOP (16.26 ± 2.98). Conclusion: Based on the present RCT, yoga-based ocular exercises practiced here cannot be recommended for management of raised IOP in glaucoma patients. Further larger studies are warranted with yoga-based interventions in patients with glaucoma. Clinical Trial Registration Number CTRI/2016/03/006703
Tratak(Yogic Ocular Exercise)对青光眼眼压的影响:随机对照试验
引言:在健康受试者中,眼压(IOP)是通过睫状体持续产生房水和通过两种引流途径(小梁网和葡萄膜巩膜流出)持续流出之间的动态平衡来维持的。在这里,我们假设瑜伽眼部运动,包括眼外肌肉运动和改良Tratak Kriya(mTK),可能会降低青光眼患者的眼压和压力,提高生活质量。方法:对青光眼患者(对照组和干预组)进行平行的双臂随机对照试验(RCT)。对照组患者接受标准药物治疗,干预组患者进行为期4周的瑜伽生活方式干预(YBLI),作为标准药物治疗的附加治疗。所有参与者在基线第1天、第14天(D14)和第28天(D28)进行评估。每组至少招募30名患者。结果:我们没有观察到两组在任何时间点右眼或左眼的平均眼压(IOP-r)以及皮质醇水平和生活质量有任何统计学意义的差异。然而,与基线眼压(16.26±2.98)相比,干预组在D14(15.54±2.81 mmHg)和D28(15.24±3.1 mmHg)时的眼压-r分别降低了,P=0.006和0.001。有必要对青光眼患者进行基于瑜伽的干预进行更大规模的研究。临床试验注册号CTRI/2016/03/006703
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来源期刊
International Journal of Yoga
International Journal of Yoga INTEGRATIVE & COMPLEMENTARY MEDICINE-
自引率
12.50%
发文量
37
审稿时长
24 weeks
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