Effectiveness of Anodal Transcranial Direct Current Stimulation of Left Dorsolateral Prefrontal Cortex in Facial Emotion Recognition and Clinical Symptoms of Boys with Autism Spectrum Disorder

IF 0.5 Q4 PSYCHIATRY
Giti Nazari, M. Mousavi, Vahid Sadeghi-Firoozabadi
{"title":"Effectiveness of Anodal Transcranial Direct Current Stimulation of Left Dorsolateral Prefrontal Cortex in Facial Emotion Recognition and Clinical Symptoms of Boys with Autism Spectrum Disorder","authors":"Giti Nazari, M. Mousavi, Vahid Sadeghi-Firoozabadi","doi":"10.5812/ijpbs-121995","DOIUrl":null,"url":null,"abstract":"Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a deficit in communication and social skills, stereotypical and repetitive patterns of behaviors, interests, and activities. The gold standard treatment, behavioral therapy, imposes a great cost on families, and its efficacy depends on the life stage at which the therapy is started. As an alternative treatment, the efficacy and safety of transcranial direct current stimulation (tDCS) have been investigated in different patient groups; however, its efficacy on facial emotion recognition (FER) has not been investigated in children with ASD. Objectives: We investigated the effectiveness of anodal tDCS of the left dorsolateral prefrontal cortex (DLPFC) in FER and clinical symptoms of children with ASD. Methods: Twenty-four boys with ASD were selected from a school in Tehran, Iran. The eligible participants were randomized to receive the intervention (15 minutes of electrical stimulation) or not (20 seconds with device-off; control group). The emotion recognition task and autism treatments evaluation checklist (ATEC) were evaluated before and after the intervention and compared using the mixed ANOVA test. Results: Eleven boys in each group completed the study. The groups were similar regarding mean age, ASD severity, and intelligence quotient. The interactive effect of group and time was significant on both scales (emotion recognition task and ATEC). Conclusions: Anodal tDCS of DLPFC is an effective therapeutic method for specific behaviors, including FER, in school-aged boys with ASD. Further studies are required to suggest this treatment as a safe and effective strategy in children with ASD.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian Journal of Psychiatry and Behavioral Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5812/ijpbs-121995","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a deficit in communication and social skills, stereotypical and repetitive patterns of behaviors, interests, and activities. The gold standard treatment, behavioral therapy, imposes a great cost on families, and its efficacy depends on the life stage at which the therapy is started. As an alternative treatment, the efficacy and safety of transcranial direct current stimulation (tDCS) have been investigated in different patient groups; however, its efficacy on facial emotion recognition (FER) has not been investigated in children with ASD. Objectives: We investigated the effectiveness of anodal tDCS of the left dorsolateral prefrontal cortex (DLPFC) in FER and clinical symptoms of children with ASD. Methods: Twenty-four boys with ASD were selected from a school in Tehran, Iran. The eligible participants were randomized to receive the intervention (15 minutes of electrical stimulation) or not (20 seconds with device-off; control group). The emotion recognition task and autism treatments evaluation checklist (ATEC) were evaluated before and after the intervention and compared using the mixed ANOVA test. Results: Eleven boys in each group completed the study. The groups were similar regarding mean age, ASD severity, and intelligence quotient. The interactive effect of group and time was significant on both scales (emotion recognition task and ATEC). Conclusions: Anodal tDCS of DLPFC is an effective therapeutic method for specific behaviors, including FER, in school-aged boys with ASD. Further studies are required to suggest this treatment as a safe and effective strategy in children with ASD.
经颅阳极直流电刺激左背外侧前额叶皮层对自闭症谱系障碍男孩面部情绪识别和临床症状的影响
背景:自闭症谱系障碍(ASD)是一种神经发育障碍,缺乏沟通和社交技能,行为、兴趣和活动模式陈旧和重复。金标准治疗,即行为疗法,给家庭带来了巨大的成本,其疗效取决于开始治疗的生活阶段。作为一种替代治疗方法,经颅直流电刺激(tDCS)的疗效和安全性已在不同的患者组中进行了研究;然而,它对ASD儿童面部情绪识别(FER)的疗效尚未得到研究。目的:我们研究了左背外侧前额叶皮层(DLPFC)阳极tDCS在FER和ASD儿童临床症状中的有效性。方法:从伊朗德黑兰的一所学校选取24名ASD男孩。符合条件的参与者被随机分组接受干预(15分钟的电刺激)或不接受干预(关闭设备20秒;对照组)。在干预前后评估情绪识别任务和自闭症治疗评估清单(ATEC),并使用混合方差分析测试进行比较。结果:每组11名男孩完成了研究。两组在平均年龄、ASD严重程度和智商方面相似。在两个量表(情绪识别任务和ATEC)上,组和时间的交互作用都很显著。结论:DLPFC的肛门tDCS是治疗学龄男孩ASD特定行为(包括FER)的有效方法。需要进一步的研究来表明这种治疗方法对ASD儿童来说是一种安全有效的策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.20
自引率
10.00%
发文量
70
期刊介绍: The Iranian Journal of Psychiatry and Behavioral Sciences (IJPBS) is an international quarterly peer-reviewed journal which is aimed at promoting communication among researchers worldwide and welcomes contributions from authors in all areas of psychiatry, psychology, and behavioral sciences. The journal publishes original contributions that have not previously been submitted for publication elsewhere. Manuscripts are received with the understanding that they are submitted solely to the IJPBS. Upon submission, they become the property of the Publisher and that the data in the manuscript have been reviewed by all authors, who agree to the analysis of the data and the conclusions reached in the manuscript. The Publisher reserves copyright and renewal on all published material and such material may not be reproduced without the written permission of the Publisher. Statements in articles are the responsibility of the authors.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信