Comparison of Serum Vitamin D Levels with Glucose, Lipid, and the Other Biochemical Parameters: A Cross-Sectional Study

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL
Y. Sezgin, Y. Hacıoğlu, A. Kaplan
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引用次数: 0

Abstract

"Since vitamin D is synthesized from cholesterol, it is claimed to be associated with insulin resistance, suggesting that there may be an association between vitamin D glucose and lipids. For this reason, we aimed to investigate a relationship between vitamin D and biochemical parameters, including glucose and lipids. This cross-sectional study included 198 patients .admitted to the family medicine outpatient clinic between June and December 2016. There was no significant correlation between vitamin D and serum glucose, total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, calcium, magnesium, sodium, TSH, and body mass index values in both men and women. There was a correlation between vitamin D and total cholesterol and LDL cholesterol levels in the younger subjects below 41 years (p=0.002). Regression analysis with other variables showed no statistical significance between vitamin D levels on LDL-C levels (P=0.309). Despite previous studies, our study did not confirm the effects of vitamin D on serum glucose, lipid, calcium, and other biochemical parameters. However, these results suggest that the standard up-to-date literature showing the relationship between vitamin D and various metabolic and hormonal disorders may need to be confirmed by new large-scale studies. "
血清维生素D水平与葡萄糖、脂质和其他生化参数的比较:一项横断面研究
“由于维生素D是由胆固醇合成的,它被认为与胰岛素抵抗有关,这表明维生素D葡萄糖和脂质之间可能存在关联。因此,我们旨在研究维生素D与包括葡萄糖和脂质在内的生化参数之间的关系。这项横断面研究包括198名患者2016年6月至12月期间的门诊。维生素D与男性和女性的血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白、钙、镁、钠、TSH和体重指数之间没有显著相关性。在41岁以下的年轻受试者中,维生素D与总胆固醇和低密度脂蛋白胆固醇水平之间存在相关性(p=0.002)。与其他变量的回归分析显示,维生素D水平与低密度脂素胆固醇水平之间没有统计学意义(p=0.009)。尽管之前有研究,但我们的研究没有证实维生素D对血糖、脂质、钙,以及其他生物化学参数。然而,这些结果表明,显示维生素D与各种代谢和激素紊乱之间关系的标准最新文献可能需要通过新的大规模研究来证实。“
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来源期刊
Romanian Journal of Military Medicine
Romanian Journal of Military Medicine MEDICINE, GENERAL & INTERNAL-
自引率
33.30%
发文量
2
审稿时长
12 weeks
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