The Prevalence of Pulmonary Arterial Hypertension in Patients with Beta Thalassemia Major.

IF 0.7 4区医学 Q4 HEMATOLOGY

Indian Journal of Hematology and Blood Transfusion Pub Date : 2024-01-01 Epub Date: 2023-07-08 DOI:10.1007/s12288-023-01678-7

Masoumeh Kahnoji, Saeid Bitaraf, Narjes Soltani, Hamidreza Esmaeili-Nadimi

{"title":"The Prevalence of Pulmonary Arterial Hypertension in Patients with Beta Thalassemia Major.","authors":"Masoumeh Kahnoji, Saeid Bitaraf, Narjes Soltani, Hamidreza Esmaeili-Nadimi","doi":"10.1007/s12288-023-01678-7","DOIUrl":null,"url":null,"abstract":"Pulmonary arterial hypertension (PAH) remains a concern in patients with Beta thalassemia major (TM). However, this study aims to investigate the prevalence of PAH in TM patients in Kerman City placed in the south of Iran. In this cross-sectional study on 271 IranianBeta-thalassemia patients (mean age 19.8 <math><mo>±</mo></math> 7.9 in the range 10-60), Age, sex, weekly deferral taking, the number of blood transfusion in a month, and last echocardiography report data was gathered from every patient's file. SPSS for Windows (version 21) was used for analysis. According to the results, the prevalence of PAH was 10.3% (28 patients). PAH had significant associations with weekly deferral consumption (P = 0.028), ferritin serum level (P = 0.001), and ejection fraction (EF) (P = 0.001). PAH is positively associated with deferral consumption and is negatively associated with EF (respectively, P = 0.031, P = 0.001). It is very important to consider prevention and treatment for decreasing the mortality and morbidity of PAH patients in health planning and policy.","PeriodicalId":49188,"journal":{"name":"Indian Journal of Hematology and Blood Transfusion","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10831030/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Hematology and Blood Transfusion","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12288-023-01678-7","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/7/8 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"HEMATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Pulmonary arterial hypertension (PAH) remains a concern in patients with Beta thalassemia major (TM). However, this study aims to investigate the prevalence of PAH in TM patients in Kerman City placed in the south of Iran. In this cross-sectional study on 271 IranianBeta-thalassemia patients (mean age 19.8 $\pm$ 7.9 in the range 10-60), Age, sex, weekly deferral taking, the number of blood transfusion in a month, and last echocardiography report data was gathered from every patient's file. SPSS for Windows (version 21) was used for analysis. According to the results, the prevalence of PAH was 10.3% (28 patients). PAH had significant associations with weekly deferral consumption (P = 0.028), ferritin serum level (P = 0.001), and ejection fraction (EF) (P = 0.001). PAH is positively associated with deferral consumption and is negatively associated with EF (respectively, P = 0.031, P = 0.001). It is very important to consider prevention and treatment for decreasing the mortality and morbidity of PAH patients in health planning and policy.

查看原文本刊更多论文

β地中海贫血患者肺动脉高压的患病率

重型β地中海贫血（TM）患者的肺动脉高压（PAH）仍然是一个令人担忧的问题。然而，本研究旨在调查伊朗南部克尔曼市重型地中海贫血患者中 PAH 的患病率。这项横断面研究的对象是 271 名伊朗重型β地中海贫血患者（平均年龄为 19.8 ± 7.9 岁，范围在 10-60 岁之间），研究人员从每位患者的档案中收集了他们的年龄、性别、每周延期服药情况、一个月内输血次数以及最后一次超声心动图检查报告等数据。分析采用 SPSS for Windows（21 版）。结果显示，PAH 患病率为 10.3%（28 名患者）。PAH 与每周的推迟消耗量（P = 0.028）、铁蛋白血清水平（P = 0.001）和射血分数（EF）（P = 0.001）有明显相关性。PAH与延期消费呈正相关，与射血分数呈负相关（分别为P = 0.031和P = 0.001）。在卫生规划和政策中考虑预防和治疗以降低 PAH 患者的死亡率和发病率非常重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Indian Journal of Hematology and Blood Transfusion HEMATOLOGY-

CiteScore

1.70

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Indian Journal of Hematology and Blood Transfusion is a medium for propagating and exchanging ideas within the medical community. It publishes peer-reviewed articles on a variety of aspects of clinical hematology, laboratory hematology and hemato-oncology. The journal exists to encourage scientific investigation in the study of blood in health and in disease; to promote and foster the exchange and diffusion of knowledge relating to blood and blood-forming tissues; and to provide a forum for discussion of hematological subjects on a national scale. The Journal is the official publication of The Indian Society of Hematology & Blood Transfusion.