Research status and progress of dissociated optic nerve fiber layer after internal limiting membrane peeling

Q4 Medicine
Xueting Yu, J. Tao, Lijun Shen
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引用次数: 0

Abstract

Dissociated optic nerve fiber layer (DONFL) appearance is consists of numerous arcuate dark striae within the posterior pole in the direction of the optic nerve fibers. And on the cross-sectional image, DONFL was correspond to inner retinal dimples. It mainly occurs after the internal limiting membrane (ILM) peeling due to the direct damage on the local retina and the broad tractional effect on the posterior retina during membrane peeling. DONFL appearance is considered to be a spontaneous and delayed morphologic change with a subclinical nature, and appears to have little effect on retinal function. In addition to avoiding the removal of ILM and reducing the area of ILM peeling, a novel technique for reposition of the fixed ILM flap with the assistance of perfluoro-n-octane and the temporal inverted ILM flap technique can also be used to prevent and reduce the occurrence of DONFL appearance. Further studies on its development, clinical features and clinical significance are still required. Key words: Retinal diseases/surgery; Vitreoretinal surgery; Review; Optic nerve fiber layer
内限制膜剥离后视神经纤维游离层的研究现状与进展
分离的视神经纤维层(DONFL)外观由视神经纤维方向的后极内的许多弓形深色条纹组成。在横截面图像上,DONFL对应于视网膜内部的凹坑。它主要发生在内界膜(ILM)剥离之后,这是由于在膜剥离过程中对局部视网膜的直接损伤和对后部视网膜的广泛牵引作用。DONFL的出现被认为是一种亚临床性质的自发和延迟的形态学变化,似乎对视网膜功能没有什么影响。除了避免去除ILM和减少ILM剥离面积外,还可以使用一种在全氟正辛烷的帮助下重新定位固定的ILM皮瓣的新技术和颞侧倒置的ILM皮瓣技术来预防和减少DONFL出现的发生。对其发展、临床特征和临床意义仍需进一步研究。关键词:视网膜疾病/外科;玻璃体视网膜手术;评审;视神经纤维层
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来源期刊
中华眼底病杂志
中华眼底病杂志 Medicine-Ophthalmology
CiteScore
0.40
自引率
0.00%
发文量
5383
期刊介绍: Chinese Journal of Ocular Fundus Diseases is the only scientific journal in my country that focuses on reporting fundus diseases. Its purpose is to combine clinical and basic research, and to give equal importance to improvement and popularization. It comprehensively reflects the leading clinical and basic research results of fundus disease disciplines in my country; cultivates professional talents in fundus disease, promotes the development of fundus disease disciplines in my country; and promotes academic exchanges on fundus disease at home and abroad. The coverage includes clinical and basic research results of posterior segment diseases such as retina, uveal tract, vitreous body, visual pathway, and internal eye diseases related to systemic diseases. The readers are medical workers and researchers related to clinical and basic research of fundus diseases. According to the journal retrieval report of the Chinese Institute of Scientific and Technological Information, the comprehensive ranking impact factor and total citation frequency of the Chinese Journal of Ocular Fundus Diseases have been among the best in the disciplines of ophthalmology, otolaryngology, and ophthalmology in my country for many years. The papers published have been included in many important databases at home and abroad, such as Scopus, Peking University Core, and China Science Citation Database (CSCD).
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