Neurophysiological Mechanisms of Regulation of Sensomotor Reactions of Differentiation in Onthogenesis

Q4 Biochemistry, Genetics and Molecular Biology

Journal of Cellular Neuroscience and Oxidative Stress Pub Date : 2019-06-18 DOI:10.37212/JCNOS.613330

A. Palabiyik, V. S. Lizohub, N. Chernenko

{"title":"Neurophysiological Mechanisms of Regulation of Sensomotor Reactions of Differentiation in Onthogenesis","authors":"A. Palabiyik, V. S. Lizohub, N. Chernenko","doi":"10.37212/JCNOS.613330","DOIUrl":null,"url":null,"abstract":"The amplitude-frequency characteristics of the late and early components of brain- evoked potentials (EP) and the speed of motor (MK), central ( central information processing (CIP ) and sensory (SC) component of the reaction of choice 2 from 3 stimuli (RC 2-3 ), presented in mode go/nogo/gо investigated in children, teenagers and young people. It was found that the formation of sensorimotor reactions of differentiation in children, teenagers and young people is characterized by a gradual decrease in the quantities of mistakes and time of RC 2-3 , MK, SC, CIP , also latency and an increase in amplitude the evoked potential ( Е P ) . In children was invented simultaneous activation of the early ( N 1 , Р 1 , N 2 , Р 2 ) and deactivation of late (Р 3 ) Е P of the cerebral cortex and significant more mistakes and lower speed of RC 2-3 , MC, SC, CIP which indicates the presence of cortical-subcortical dysfunction of the sensor-motor system. In young people high speed of RC 2-3 , MC, SC, CIP and a smaller quantities of mistakes coincided with short latencies and a high amplitude of inter- peak intervals N 1 -P 2 and P 2 -N 2 and Р 300 . The results testify the formation of neurophysiological mechanisms of sensory-motor differentiation reactions happens with participation , mainly, of the early (N 1 , P 1 , N 2 , P 2 ) component s of children whereas late components of the Е P (P 3 ) are more actively involved in young people .","PeriodicalId":37782,"journal":{"name":"Journal of Cellular Neuroscience and Oxidative Stress","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cellular Neuroscience and Oxidative Stress","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37212/JCNOS.613330","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}

引用次数: 5

Abstract

The amplitude-frequency characteristics of the late and early components of brain- evoked potentials (EP) and the speed of motor (MK), central ( central information processing (CIP ) and sensory (SC) component of the reaction of choice 2 from 3 stimuli (RC 2-3 ), presented in mode go/nogo/gо investigated in children, teenagers and young people. It was found that the formation of sensorimotor reactions of differentiation in children, teenagers and young people is characterized by a gradual decrease in the quantities of mistakes and time of RC 2-3 , MK, SC, CIP , also latency and an increase in amplitude the evoked potential ( Е P ) . In children was invented simultaneous activation of the early ( N 1 , Р 1 , N 2 , Р 2 ) and deactivation of late (Р 3 ) Е P of the cerebral cortex and significant more mistakes and lower speed of RC 2-3 , MC, SC, CIP which indicates the presence of cortical-subcortical dysfunction of the sensor-motor system. In young people high speed of RC 2-3 , MC, SC, CIP and a smaller quantities of mistakes coincided with short latencies and a high amplitude of inter- peak intervals N 1 -P 2 and P 2 -N 2 and Р 300 . The results testify the formation of neurophysiological mechanisms of sensory-motor differentiation reactions happens with participation , mainly, of the early (N 1 , P 1 , N 2 , P 2 ) component s of children whereas late components of the Е P (P 3 ) are more actively involved in young people .

查看原文本刊更多论文

胚胎发生过程中感觉运动分化反应调控的神经生理学机制

在儿童、青少年和青少年中，研究了脑诱发电位（EP）的晚期和早期成分的幅频特征，以及从3种刺激中选择2种反应（RC 2-3）的运动速度（MK）、中枢信息处理（CIP）和感觉（SC）成分。研究发现，儿童、青少年和年轻人分化的感觉运动反应的形成特点是RC 2-3、MK、SC、CIP的错误数量和时间逐渐减少，潜伏期和诱发电位幅度增加。在儿童中，发明了大脑皮层早期（N1，Р1，N2，Р2）和晚期（Р3）的同时激活，以及RC 2-3、MC、SC、CIP的显著更多错误和更低速度，这表明传感器-运动系统存在皮层下功能障碍。在年轻人中，RC 2-3、MC、SC、CIP的高速度和少量错误与N1-P2、P2-N2和Р300峰间间隔的短潜伏期和高振幅一致。结果证明，感觉运动分化反应的神经生理学机制的形成主要发生在儿童早期（N1，P1，N2，P2）成分s的参与下，而青年人则更积极地参与了后期（E3）成分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Cellular Neuroscience and Oxidative Stress Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

1.10

自引率

0.00%

发文量

期刊介绍： Journal of Cellular Neuroscience and Oxidative Stress isan online journal that publishes original research articles, reviews and short reviews on themolecular basisofbiophysical,physiological and pharmacological processes thatregulate cellular function, and the control or alteration of these processesby theaction of receptors, neurotransmitters, second messengers, cation, anions,drugsor disease. Areas of particular interest are four topics. They are; 1. Ion Channels (Na+-K+Channels, Cl– channels, Ca2+channels, ADP-Ribose and metabolism of NAD+,Patch-Clamp applications) 2. Oxidative Stress (Antioxidant vitamins, antioxidant enzymes, metabolism of nitric oxide, oxidative stress, biophysics, biochemistry and physiology of free oxygen radicals) 3. Interaction Between Oxidative Stress and Ion Channels in Neuroscience (Effects of the oxidative stress on the activation of the voltage sensitive cation channels, effect of ADP-Ribose and NAD+ on activation of the cation channels which are sensitive to voltage, effect of the oxidative stress on activation of the TRP channels in neurodegenerative diseases such Parkinson’s and Alzheimer’s diseases) 4. Gene and Oxidative Stress (Gene abnormalities. Interaction between gene and free radicals. Gene anomalies and iron. Role of radiation and cancer on gene polymorphism)