Unraveling scrub encephalitis: A study on the clinical profile and investigations of scrub encephalitis

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
C. Sukumar, N. Bolanthakodi, Laawa Lakhmani, Ajit Singh, S. Vidyasagar
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引用次数: 0

Abstract

Introduction: Scrub encephalitis (SE) is one of the known causes of acute encephalitis syndrome (AES). Although central nervous system involvement is known in scrub typhus, its association with AES is less understood and lesser diagnosed. In the absence of a point of care test for scrub typhus, cases of SE can be easily missed. A clinical approach using detailed history and clinical profiling of SE will help to diagnose SE in our region, using minimum resources, within a reasonable period. Aims: To analyze the clinical spectrum in patients of SE and to evaluate the investigations required to diagnose SE. Methodology: This is a retrospective study that analyzed Scrub typhus patients over 2 years from January 2018 to December 2019. A total of 370 patients were screened and 23 patients who satisfied the study criteria were included in the study and analyzed. Results: Among the cases of scrub typhus admitted in the hospital, the prevalence of SE was 6%. The most common presenting complaint was fever in 21 patients (91%) followed by altered sensorium in 16 (70%) and seizures in 9 patients (39%). An eschar was noted in 66% of the cases. The mean Glasgow Coma scale was 11 among the cases with almost 70% of cases showing signs of meningeal irritation. Organ involvement was noted as thrombocytopenia in 21 patients (91%), 16 patients (69%) with jaundice, and 1 (4%) with acute kidney injury. Conclusion: SE is an AES which, if detected early, is easily treatable with no residual neurological sequelae. Hence, identification of this condition and prompt diagnosis of SE becomes crucial to the management of this complication of scrub typhus.
揭示丛林脑炎:丛林脑炎的临床概况和调查研究
简介:丛林脑炎(SE)是急性脑炎综合征(AES)的已知病因之一。尽管已知丛林斑疹伤寒涉及中枢神经系统,但其与AES的关系尚不清楚,诊断也较少。在没有擦洗斑疹伤寒护理点测试的情况下,SE病例很容易被遗漏。使用详细的SE病史和临床特征的临床方法将有助于在合理的时间内使用最少的资源诊断我们地区的SE。目的:分析SE患者的临床谱,并评估诊断SE所需的调查。方法:这是一项回顾性研究,分析了2018年1月至2019年12月的2年时间内的恙虫病患者。共筛选了370名患者,23名符合研究标准的患者被纳入研究并进行分析。结果:在住院的恙虫病患者中,SE的患病率为6%。最常见的主诉是21名患者(91%)发烧,其次是16名患者(70%)感觉异常和9名患者(39%)癫痫发作。66%的病例出现焦痂。格拉斯哥昏迷的平均评分为11,其中近70%的病例表现出脑膜刺激的迹象。21名患者(91%)、16名黄疸患者(69%)和1名急性肾损伤患者(4%)的器官受累为血小板减少。结论:SE是一种AES,如果早期发现,很容易治疗,没有残留的神经后遗症。因此,识别这种情况并及时诊断SE对于治疗这种丛林斑疹伤寒并发症至关重要。
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来源期刊
Indian Journal of Medical Specialities
Indian Journal of Medical Specialities MEDICINE, GENERAL & INTERNAL-
自引率
16.70%
发文量
51
期刊介绍: The Indian Journal of Medical Specialities is an all-encompassing peer-reviewed quarterly journal. The journal publishes scholarly articles, reviews, case reports and original research papers from medical specialities specially pertaining to clinical patterns and epidemiological profile of diseases. An important highlight is the emphasis on undergraduate and postgraduate medical education including various aspects of scientific paper-writing. The journal gives priority to research originating from the developing world, including from the tropical regions of the world. The journal also publishes special issues on health topics of current interest. The Indian Journal of Medical Specialities is one of the very few quality multispeciality scientific medical journals.
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