How Effective Is Aerobic Exercise Training in Improving Aerobic Capacity After Heart Transplant? A Systematic Review and Meta-analysis

Keriann Groen, P. Robison, Annie Xiong, Kent E. Irwin, Amy B Stein, C. C. Evans
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引用次数: 2

Abstract

Supplemental Digital Content is Available in the Text. Purpose: Studies suggest that additional exercise (Ex) training beyond “usual care” increases peak VO2 in people post-heart transplant (HTx); however, no recent studies have quantified improvements or compared moderate-intensity aerobic Ex (MOD) to high-intensity interval training (HIIT). The purpose of this study was to quantify improvements in VO2 for patients post-HTx undergoing additional Ex training and compare effectiveness of MOD to HIIT. Methods: Inclusion criteria were: randomized clinical trials, systematic reviews, or meta-analyses published between 2008 to 2018, subjects post-HTx, participated in an aerobic Ex program beyond usual care, and reported peak VO2. Results: A total of 242 records were obtained and 7 randomized clinical trials were reviewed. The average PEDro score was 4.86 (range 2–7). The within-group weighted mean difference (WMD) in peak VO2 comparing baseline to post-training for the Ex group = 3.3 (0.5) ml/kg/min and for the control group = −0.2 (0.2) ml/kg/min. The between-group WMD in peak VO2 = 3.5 (7.9) ml/kg/min, Hedge's g = 0.606 (95% confidence intervals = 0.337–0.874), P < .001, favoring Ex. Comparison between Ex protocols indicated that there was no difference between HIIT and MOD (Q = 1.83, P = .176). Conclusions: Physical therapists should challenge patients post-HTx with aerobic Ex that goes beyond usual post-HTx care and should consider incorporating HIIT into the treatment plan or home program to maximize the benefits of rehabilitation when possible.
有氧运动训练对提高心脏移植后的有氧能力有多有效?系统回顾和荟萃分析
补充数字内容可在文本中获得。目的:研究表明,在“常规护理”之外的额外运动(Ex)训练可以增加心脏移植后患者的峰值VO2;然而,最近没有研究量化改善或比较中等强度有氧Ex (MOD)与高强度间歇训练(HIIT)。本研究的目的是量化htx后接受额外Ex训练的患者VO2的改善,并比较MOD与HIIT的有效性。方法:纳入标准为:2008年至2018年间发表的随机临床试验、系统评价或荟萃分析、htx后受试者、参加常规护理以外的有氧Ex计划,并报告VO2峰值。结果:共获得242份记录,回顾了7项随机临床试验。平均PEDro评分为4.86(范围2-7)。实验组与训练后相比,组内VO2峰值加权平均差(WMD) = 3.3 (0.5) ml/kg/min,对照组= - 0.2 (0.2)ml/kg/min。峰VO2组间WMD = 3.5 (7.9) ml/kg/min, Hedge’s g = 0.606(95%可信区间= 0.337 ~ 0.874),P < 0.001,支持Ex。Ex方案间比较表明HIIT与MOD之间无差异(Q = 1.83, P = 0.176)。结论:物理治疗师应该对htx后患者进行有氧Ex训练,以超越通常的htx后护理,并应考虑将HIIT纳入治疗计划或家庭计划,以尽可能最大化康复效益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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