: Introduction: Population aging implies increased demands for care sanitary. The frailty of the elderly a previous step to disabili-ty, causing deterioration in the quality of life both in people who suffer, as in the caregivers. Objec-tive: Determine the relationship between frailty syndrome in the elderly with the overload primary caregiver. Material and method: Analyt-ical Observational study design. It included 145 older adults with a primary caregiver, excluding those with cognitive impairment or severe phys-ical disability. After signing the consent, general data were interrogated; the Ensrud scales for frailty in the elderly and abbreviated Zarit scales for caregiver overload were applied independent-ly. Descriptive analysis, chi square, Mann-Whit-ney and Spearman correlation, obtained with SPSS version 22 program, was considered signif-icant difference with p < 0.05. Results: 61.4% of the older adults are women, age 77 ± 7 years, 59% married, 28% were classified as fragile and 50% as pre-fragile. Sex, age, schooling and comorbid-ities were associated with frailty. 70% of caregiv-ers are women, 41% have have intense overload, and caregiver wear was associated within the elderly. Conclusion: The level of caregiver attrition had a moderate positive correlation with frailty in the elderly.