Clinical effect of microsurgical operation combined with liquid nitrogen cryotherapy on squamous cell carcinoma in elderly patients

中华老年医学杂志 Pub Date : 2019-12-14 DOI:10.3760/CMA.J.ISSN.0254-9026.2019.12.018

Rui Wang, Fei-Fei Wang

{"title":"Clinical effect of microsurgical operation combined with liquid nitrogen cryotherapy on squamous cell carcinoma in elderly patients","authors":"Rui Wang, Fei-Fei Wang","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.12.018","DOIUrl":null,"url":null,"abstract":"Objective \nTo investigate the clinical effect of microsurgical operation combined with liquid nitrogen cryotherapy on squamous cell carcinoma in elderly patients. \n \n \nMethods \nForty-six patients with squamous cell carcinoma visiting dermatology department of our hospital from January 2011 to July 2014 were enrolled.They were randomizely divided into two groups: the control group(n=23)receiving a microsurgical treatment and the observation group(n=23)receiving liquid nitrogen cryotherapy as add-on to a microsurgical operation.All patients were followed up for 1-3 years.Clinical efficacy, 1-year recurrence rate, 1-year transfer rate and the survival rate were compared between the two groups. \n \n \nResults \nThe total effective rate was higher in the observation group than in the control group(91.3% vs.82.6%, P<0.05). The 1-year recurrence rate and 1-year transfer rate were lower in the observation group than in the control group(13.4% vs.17.4%, 4.3% vs.8.7%, P<0.05). \n \n \nConclusions \nThe surgery combined with liquid nitrogen cryotherapy for cutaneous squamous cell carcinoma can significantly reduce the recurrence rate and transfer rate after operation and prolong the survival time, which is worthy of further research and promotion. \n \n \nKey words: \nCrgotherapy; Skin neoplasms; Neoplasms, squamous cell","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1398-1400"},"PeriodicalIF":0.0000,"publicationDate":"2019-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华老年医学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.12.018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective To investigate the clinical effect of microsurgical operation combined with liquid nitrogen cryotherapy on squamous cell carcinoma in elderly patients. Methods Forty-six patients with squamous cell carcinoma visiting dermatology department of our hospital from January 2011 to July 2014 were enrolled.They were randomizely divided into two groups: the control group(n=23)receiving a microsurgical treatment and the observation group(n=23)receiving liquid nitrogen cryotherapy as add-on to a microsurgical operation.All patients were followed up for 1-3 years.Clinical efficacy, 1-year recurrence rate, 1-year transfer rate and the survival rate were compared between the two groups. Results The total effective rate was higher in the observation group than in the control group(91.3% vs.82.6%, P<0.05). The 1-year recurrence rate and 1-year transfer rate were lower in the observation group than in the control group(13.4% vs.17.4%, 4.3% vs.8.7%, P<0.05). Conclusions The surgery combined with liquid nitrogen cryotherapy for cutaneous squamous cell carcinoma can significantly reduce the recurrence rate and transfer rate after operation and prolong the survival time, which is worthy of further research and promotion. Key words: Crgotherapy; Skin neoplasms; Neoplasms, squamous cell

查看原文本刊更多论文

显微外科手术联合液氮冷冻治疗老年鳞状细胞癌的临床疗效

目的探讨显微外科手术联合液氮冷冻治疗老年鳞状细胞癌的临床疗效。方法选择2011年1月至2014年7月在我院皮肤科就诊的46例鳞状细胞癌患者。他们被随机分为两组：对照组（n=23）接受显微外科治疗，观察组（n=24）接受液氮冷冻治疗作为显微外科手术的补充。所有患者均进行了1-3年的随访。比较两组的临床疗效、1年复发率、1年转移率和生存率。结果观察组总有效率高于对照组（91.3%vs.82.6%，P<0.05），1年复发率和1年转移率低于对照组（13.4%vs.17.4%，4.3%vs.8.7%，P<0.05）降低术后复发率和转移率，延长生存时间，值得进一步研究和推广。关键词：Crgotherapy；皮肤肿瘤；肿瘤，鳞状细胞

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

中华老年医学杂志

自引率

0.00%

发文量

8523

期刊介绍：