Current Management and Treatment for Patients with Chronic Kidney Disease

Chon Jun Jason Choo
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Abstract

The incidence of chronic kidney disease (CKD) is rising in many parts of the world and primary care providers are poised to be the first point of contact for these patients. The optimal management of patients with CKD include early detection, cause identification, CKD progression retardation (including dietary support, blood pressure control, drug therapeutics), management of comorbid conditions, acute kidney injury prevention, and knowing when to refer for specialist care. In general, the concept of CKD progression retardation involves patient education on topics such as lifestyle modification measures, e.g., diet, to reduce burden on the kidneys and use of medications that can confer renoprotection while causing little if any side effects. The advent of SGLT2 inhibitors, nonsteroidal mineralocorticoid receptor antagonists, and new potassium binders provides our patients with new hope to further lengthen the time to end-stage kidney failure. It is therefore necessary that stakeholders involved in the care of patients with CKD understand the latest evidence to optimise care and patient wellbeing.
慢性肾脏病患者的管理和治疗现状
慢性肾脏病(CKD)的发病率在世界许多地方都在上升,初级保健提供者准备成为这些患者的第一个接触点。CKD患者的最佳管理包括早期发现、病因识别、CKD进展迟缓(包括饮食支持、血压控制、药物治疗)、合并症的管理、急性肾损伤的预防以及知道何时转诊专科护理。一般来说,CKD进展迟缓的概念涉及患者教育,主题包括改变生活方式的措施,如饮食,以减轻肾脏负担,以及使用可以提供肾脏保护的药物,同时几乎不会产生副作用。SGLT2抑制剂、非甾体盐皮质激素受体拮抗剂和新型钾结合剂的出现为我们的患者进一步延长终末期肾衰竭的时间提供了新的希望。因此,参与CKD患者护理的利益相关者有必要了解优化护理和患者健康的最新证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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