Comparison of platelet-rich fibrin and cellulose in palatal wounds after graft harvesting

Q1 Medicine

Journal of Investigative and Clinical Dentistry Pub Date : 2019-09-27 DOI:10.1111/jicd.12467

Arada Patarapongsanti, Panwadee Bandhaya, Benyapha Sirinirund, Sakornratana Khongkhunthian, Pathawee Khongkhunthian

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引用次数: 9

Abstract

Aim

The aim of the present study was to compare patient morbidity and healing outcomes of free gingival graft (FGG) harvesting at palatal donor sites and after using platelet-rich fibrin (PRF) and oxidized regenerated cellulose (ORC). FGG harvesting leaves open palatal wounds, which heal by secondary intention. Patients might experience discomfort or pain during the first 2 weeks of healing.

Methods

Eighteen participants requiring two FGG were recruited. The test and control sites were covered with PRF membrane and ORC. The complete epithelialization of the palatal wound, the percentage of wound healing, and postoperative pain were evaluated, 1, 3, and 7 days and 2, 3, and 4 weeks after surgery.

Results

Similar wound size reduction at 1 week (test: 36.87%, control: 38.78%) was found. At 2 weeks, the majority of the test group (88.89%) showed complete epithelialization, whereas 66.67% of the control group had complete epithelialization (P = .228). Pain was more prevalent in the control group (27.77%) than in the test group (11.1%) on day 1. None of the participants reported any pain or discomfort at the test sites on day 3.

Conclusions

PRF seems to reduce patient morbidity, but there is no difference in palatal wound healing (P > .05).

查看原文本刊更多论文

腭部伤口移植后富含血小板的纤维蛋白和纤维素的比较。

目的本研究的目的是比较在腭供区和使用富血小板纤维蛋白(PRF)和氧化再生纤维素(ORC)后获得游离牙龈移植物(FGG)的患者发病率和愈合结果。采集FGG会在腭部留下伤口，这些伤口是由次要意图愈合的。患者在愈合的前两周可能会感到不适或疼痛。方法招募18名需要2次FGG的受试者。试验和对照部位均覆盖PRF膜和ORC。分别于术后1、3、7天和2、3、4周评估腭创面上皮完全化情况、创面愈合百分率和术后疼痛。结果两组术后1周创面缩小率相近(实验组:36.87%，对照组:38.78%)。2周时，绝大多数试验组(88.89%)上皮完全化，而对照组(66.67%)上皮完全化(P = 0.228)。第1天，对照组(27.77%)疼痛发生率高于试验组(11.1%)。在第三天，没有参与者报告在测试部位有任何疼痛或不适。结论sprf似乎降低了患者的发病率，但在腭创面愈合方面没有差异(P < 0.05)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Investigative and Clinical Dentistry DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.90

自引率

0.00%

发文量

期刊介绍： Journal of Investigative and Clinical Dentistry (JICD) aims to publish quality, peer reviewed original research and topical reviews on all aspects of investigative and clinical dentistry and craniofacial research, including molecular studies related to oral health and disease. Although international in outlook, the Editor especially encourages papers from the Asia Pacific. The journal also aims to provide clinicians, scientists and students of dentistry with a knowledge transfer platform for rapid publication of reports through an international journal, which will be available free online until 2012. Its scope, therefore, is broad, inclusive and international, but with a particular focus on Asia Pacific. The Editor welcomes manuscripts in the following key thematic areas in oral and maxillofacial sciences: Community Dentistry and Oral Epidemiology, Conservative Dentistry, Dental Biomaterials, Dental Pedagogy, Endodontics and Traumatology, Implant Dentistry, Oral Biosciences, Oral and Maxillofacial Surgery, Oral Medicine, Oral Pathology and Oral Microbiology, Orthodontics, Oral Radiology, Oral Rehabilitation, Paedodontics, Periodontology and Periodontal Medicine.