Postoperative outcomes following surgical stabilization of rib fractures stratified by 5-factor modified frailty index

N. Saraswat, Nicole Werwie, Jin Wu, Danielle Hery, E. Saunders, Hannah Bundy, J. Elliott, B. Goslin, William B. DeVoe
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Abstract

Objectives: Surgical stabilization of rib fractures (SSRF) improves outcomes in patients with flail chest and displaced fractures with impaired pulmonary function. Elderly and frail patients with such injuries are at risk for significant morbidity and may benefit from SSRF. The 5-factor modified frailty index (mFI-5) is a validated predictor of postoperative outcomes. The purpose of this study is to evaluate the relationship between frailty and outcomes following SSRF at a tertiary care trauma center. Methods: A retrospective review of patients undergoing SSRF from 2015 to 2019. Patients over 18 years old with two or more displaced fractures were included in the study. Exclusion criteria were isolated fracture, traumatic brain injury, and pulmonary contusion. Frail patients were defined by an mFI-5 score 2 or greater. Chi-square analysis, Fischer's exact test, and Student's t-test were used for comparative analysis as appropriate. P < 0.05 was considered statistically significant. Results: One hundred and fifty-four patients met inclusion criteria. Forty-eight patients were designated frail and 106 nonfrail. The mean number of fractures was similar between frail and nonfrail groups (7.0 vs. 7.3, P = 0.685). Injury Severity Score was lower in the frail group (14.5 vs. 17.8, P = 0.02). Inpatient mortality (P = 0.312), rates of pneumonia, end-organ dysfunction, and surgical site infections were similar (P > 0.05). Intensive care unit admission (47.9% vs. 29.2%, P = 0.025) and tracheostomy rates (P = 0.009) were increased in the frail group. Frailty also increased the risk of prolonged mechanical ventilation >48 h on multivariate analysis. Conclusion: Frail patients, stratified using mFI 5 score, experienced similar rates of multiple postoperative outcomes, including mortality, but had increased rates of prolonged ventilation and tracheostomy. Despite observed but expected increased morbidity in these patients, the similar complication and mortality rates suggest a role for surgical stabilization of severe rib fractures in frail patients.
应用5因子改良虚弱指数对肋骨骨折手术稳定后的术后结果进行分层
目的:肋骨骨折的外科稳定(SSRF)可改善连枷胸和移位性骨折伴肺功能受损患者的预后。患有此类损伤的年老体弱患者有严重发病的风险,可能受益于SSRF。5因子改良虚弱指数(mFI-5)是一种有效的术后结果预测指标。本研究的目的是评估三级护理创伤中心SSRF后虚弱与结果之间的关系。方法:对2015年至2019年接受SSRF的患者进行回顾性分析。18岁以上有两处或两处以上移位性骨折的患者被纳入研究。排除标准为孤立性骨折、创伤性脑损伤和肺挫伤。虚弱患者的定义是mFI-5评分为2或更高。卡方分析、Fischer精确检验和Student t检验用于适当的比较分析。P<0.05被认为具有统计学意义。结果:154名患者符合入选标准。48名患者被指定为虚弱患者,106名患者为非疲劳患者。虚弱组和非虚弱组的平均骨折数相似(7.0 vs.7.3,P=0.685)。虚弱组的损伤严重程度评分较低(14.5 vs.17.8,P=0.02)。住院死亡率(P=0.312)、肺炎发病率、末端器官功能障碍,手术部位感染相似(P>0.05)。虚弱组的重症监护病房入院率(47.9%对29.2%,P=0.025)和气管切开率(P=0.009)增加。多变量分析显示,虚弱也增加了延长机械通气>48小时的风险。结论:使用mFI 5评分对虚弱患者进行分层,其多种术后结果(包括死亡率)的发生率相似,但延长通气和气管造口术的发生率增加。尽管观察到但预计这些患者的发病率会增加,但相似的并发症和死亡率表明,手术稳定虚弱患者的严重肋骨骨折具有一定作用。
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