Cytology as a reliable method of verifying the diagnosis at the preoperative stage

G. R. Aizetullova, V. Osipov
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Abstract

The case histories of 414 patients who were operated on for mild diseases of the thyroid gland (DTH) were retrospectively studied. The study is aimed at studying the cytological material in the preoperative period and the comparative assessment of the postoperative histological material of patients operated on for the thyroid gland. As a result of the study, it was found that the share of nodular goiter with euthyroid function (UEZ) and multinodular euthyroid goiter (MUEZ) accounts for 269 patients, which is 65%. In 87 patients (21%), diffuse-toxic goiter (DTG) and nodular toxic goiter with the formation of functional autonomy (FA) were revealed; autoimmune thyroiditis (AIT) in 58 cases (14%). All 414 patients with tonic aspiration biopsy of the thyroid gland showed good changes in the cytological material. After the diagnosis, preoperative preparation, 294 patients (71%) out of 414 underwent thyroidectmia with DTZ, FA, with MUEZ and a significant increase in thyroid gland volume. Hemityroidectomy was performed in 178 patients (29%) with one-sided nodular lesion of the thyroid gland with preserved normal hormonal background. In 94% of cases, there is a coincidence of cytological and histological studies, a benign result of a biopsy material was confirmed in 389 patients. In 6% of cases (25 patients), there is a discrepancy between cytological and histological studies.
细胞学作为一种可靠的方法,验证诊断在术前阶段
回顾性分析414例甲状腺轻症手术患者的临床资料。本研究旨在研究甲状腺手术患者术前细胞学资料及术后组织学资料的比较评估。研究结果发现,结节性甲状腺肿伴甲状腺功能正常(UEZ)和多结节性甲状腺功能正常(MUEZ)患者占269例,占65%。87例(21%)患者表现为弥漫性中毒性甲状腺肿(DTG)和结节性中毒性甲状腺肿(FA)形成;自身免疫性甲状腺炎(AIT) 58例(14%)。414例甲状腺强直穿刺活检患者细胞学资料均有良好改变。诊断、术前准备后,414例患者中有294例(71%)出现甲状腺功能减退,伴DTZ、FA、MUEZ,甲状腺体积明显增加。178例(29%)单侧甲状腺结节性病变患者行半甲状腺切除术。在94%的病例中,细胞学和组织学检查结果一致,389例患者活检结果证实为良性。在6%的病例(25例)中,细胞学和组织学检查存在差异。
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