Executive Function Assessment in Patients With Idiopathic Generalized Epilepsy: Applyingthe Frontal Assessment Battery

International Clinical Neuroscience Journal Pub Date : 2021-03-27 DOI:10.34172/icnj.2021.17

Marjan Asadollahi, Mahrooz Roozbeh, Amin Edalatkhah, Mehrdad Roozbeh, Nasim Mirzaei, M. Rostami, Leila Simani

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引用次数: 1

Abstract

Background: Executive dysfunction is seen in idiopathic generalized epilepsy (IGE). The Frontal Assessment Battery (FAB) is a short neuropsychological instrument designed in clinical settings to evaluate frontal lobe activity. We aimed to assess the clinical use of FAB in patients with IGE for to detect executive impairment. Method: In this study, 30 patients with IGE and 30 age- and sex-matched healthy controls were included. The presence and severity of executive dysfunction was investigated with FAB. Cognitive flexibility, decision making, working memory, and general intelligence level were examined using Wisconsin Card Sorting Task (WCST), Iowa Gambling Task (IGT), N-back, and Wechsler Adult Intelligence Scale, respectively. In patients with IGE, FAB results were related to their neuropsychological task performance. Results: The FAB score in patients with IGE was significantly lower compared to healthy participants. In motor programming tasks, patients with IGE performed substantially worse. However, no correlation was found between FAB and neuropsychological task and clinical characteristics. Conclusion: Executive dysfunction was present in patients with IGE and FAB may be used in these patients as an effective tool for evaluating frontal lobe function.

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应用正面评估组对特发性全身性癫痫患者执行功能的评估

背景:执行功能障碍见于特发性全身性癫痫(IGE)。额叶评估电池(FAB)是一个短的神经心理学仪器设计在临床设置评估额叶活动。我们的目的是评估FAB在IGE患者中用于检测执行功能障碍的临床应用。方法:本研究纳入30例IGE患者和30例年龄、性别匹配的健康对照。用FAB检测执行功能障碍的存在和严重程度。采用威斯康辛卡片分类任务(WCST)、爱荷华赌博任务(IGT)、N-back和韦氏成人智力量表分别考察认知灵活性、决策能力、工作记忆和一般智力水平。在IGE患者中，FAB结果与其神经心理任务表现有关。结果:IGE患者的FAB评分明显低于健康人。在运动编程任务中，IGE患者的表现明显更差。然而，FAB与神经心理任务和临床特征没有相关性。结论:IGE患者存在执行功能障碍，FAB可作为评估患者额叶功能的有效工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Clinical Neuroscience Journal

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审稿时长

4 weeks