Evaluation of Laboratory Variables Related to Diffuse Axonal Injury: A Cross-Sectional Study

IF 0.4 Q4 NEUROSCIENCES

Archives of Neuroscience Pub Date : 2022-07-02 DOI:10.5812/ans-127451

M. Hatefi, Khalil Komlakh

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引用次数: 1

Abstract

Background: Diffuse axonal injury (DAI) is an injury that occurs after the onset of traumatic brain injury (TBI), leading to many problems for patients and imposing high costs on the treatment system. Objectives: This study was conducted to investigate the status of laboratory variables in patients with DAI. Methods: This cross-sectional study included 140 patients. Data collection tools were a demographic profile form and magnetic resonance imaging (MRI). Laboratory tests, including glucose, LDL-C, HDL-C, total cholesterol, triglycerides, Hb, HCT, PT, PTT, INR, BUN, creatinine, and CRP were evaluated. Also, specialized devices were used to study the laboratory and radiology variables. Results: Most (61.5%) of the patients were male, 47.1% had a non-governmental occupation, and 55.7% were less than 30 years old. Also, in 87.9% of cases, traffic accidents were the cause of DAI and in 65% of patients, the Glasgow Coma Scale (GCS) was less than 7. In all the laboratory variables differences were observed between the experimental and the control groups. Conclusions: The laboratory variables in patients with DAI had a statistically significant difference compared to the case group, which indicates the negative effect of DAI on laboratory variables. Further studies are required to confirm our results.

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评估与弥漫性轴索损伤相关的实验室变量:一项横断面研究

背景：弥漫性轴索损伤（DAI）是一种发生在创伤性脑损伤（TBI）发作后的损伤，给患者带来了许多问题，并给治疗系统带来了高昂的成本。目的：本研究旨在调查DAI患者的实验室变量状况。方法：这项横断面研究包括140名患者。数据收集工具是人口统计资料表和磁共振成像（MRI）。评估实验室测试，包括葡萄糖、LDL-C、HDL-C、总胆固醇、甘油三酯、Hb、HCT、PT、PTT、INR、BUN、肌酐和CRP。此外，还使用了专门的设备来研究实验室和放射学变量。结果：男性占61.5%，非政府职业占47.1%，30岁以下占55.7%。此外，在87.9%的病例中，交通事故是DAI的原因，在65%的患者中，格拉斯哥昏迷量表（GCS）小于7。在所有实验室变量中，观察到实验组和对照组之间的差异。结论：DAI患者的实验室变量与病例组相比有统计学意义的差异，这表明DAI对实验室变量的负面影响。需要进一步的研究来证实我们的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Neuroscience NEUROSCIENCES-

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期刊介绍： Archives of neuroscience is a clinical and basic journal which is informative to all practitioners like Neurosurgeons, Neurologists, Psychiatrists, Neuroscientists. It is the official journal of Brain and Spinal Injury Research Center. The Major theme of this journal is to follow the path of scientific collaboration, spontaneity, and goodwill for the future, by providing up-to-date knowledge for the readers. The journal aims at covering different fields, as the name implies, ranging from research in basic and clinical sciences to core topics such as patient care, education, procuring and correct utilization of resources and bringing to limelight the cherished goals of the institute in providing a standard care for the physically disabled patients. This quarterly journal offers a venue for our researchers and scientists to vent their innovative and constructive research works. The scope of the journal is as far wide as the universe as being declared by the name of the journal, but our aim is to pursue our sacred goals in providing a panacea for the intractable ailments, which leave a psychological element in the daily life of such patients. This authoritative clinical and basic journal was founded by Professor Madjid Samii in 2012.