Electrocardiographic left ventricular hypertrophy in relation to peripheral and central blood pressure indices in a Nigerian population

IF 2.3 4区医学 Q2 PERIPHERAL VASCULAR DISEASE

Blood Pressure Pub Date : 2019-07-27 DOI:10.1080/08037051.2019.1646610

A. Odili, B. Chori, B. Danladi, Wen‐Yi Yang, Zhenyu Zhang, L. Thijs, F. Wei, T. Nawrot, T. Kuznetsova, J. Staessen

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引用次数: 2

Abstract

Abstract Purpose: Previous studies that addressed whether left ventricular hypertrophy is more closely associated with central than peripheral blood pressure (BP) have been inconsistent. Radial artery wave generated by applanation tonometry and calibrated with brachial BP in 162 adult Nigerians were analysed by using generalized transfer function to derive central BP. Materials and methods: We compared the associations of ECG voltages and left ventricular hypertrophy (ECG-LVH) as continuous and binary variables respectively with central and brachial BP indices. Results: In a multivariable adjusted analysis, 1 standard deviation (SD) increase in brachial systolic, diastolic, pulse and mean arterial pressures increased the Sokolow–Lyon QRS voltage by 0.34 (CI, 0.21–0.48; p < 0.0001), 0.21 (CI, 0.07–0.36; p < 0.05); 0.22 (CI, 0.9–0.34; p < 0.001) and 0.29 (CI, 0.14–0.43) similar to (p > 0.05) corresponding Sokolow–Lyon QRS increase of 0.26 (0.12–0.40, p < 0.001); 0.14 (0.00–0.28, p < 0.05); 0.24 (0.11–0.39; p < 0.001) and 0.19 (0.05–0.34, p < 0.05) respectively observed for 1 SD increment in central pressures. The odds ratio (OR) relating ECG-LVH to 1 SD increase in brachial systolic, pulse, and mean arterial pressures were 2.62 (CI, 1.49–4.65, p < 0.001); 1.88 (CI, 1.19–2.95, p < 0.01) and 2.16 (CI, 1.22–3.82, p < 0.01) was similar to (p > 0.05) corresponding OR of 2.41 (1.33–4.36, p < 0.01); 2.04 (1.23–3.37, p < 0.01); 2.00 (1.11–3.63, p < 0.001) observed for I SD increment in central pressures. Conclusion: Central and peripheral BP are similarly associated with Sokolow–Lyon ECG voltage and hypertrophy.

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尼日利亚人群心电图左心室肥大与外周和中心血压指数的关系

摘要:目的:关于左心室肥厚与中央血压(BP)的关系是否比周围血压(BP)更密切的先前研究并不一致。本文采用广义传递函数推导中心血压，分析了162例尼日利亚成年人由压平血压计产生的桡动脉波，并与肱血压校准。材料和方法:我们将心电图电压和左心室肥厚(ECG- lvh)作为连续变量和二元变量分别与中央和肱BP指数进行比较。结果:在一项多变量调整分析中，臂膀收缩压、舒张压、脉搏压和平均动脉压每增加1个标准差(SD)， Sokolow-Lyon QRS电压增加0.34 (CI, 0.21-0.48;Sokolow-Lyon QRS相应增加0.26 (0.12-0.40,p 0.05)， OR相应增加2.41 (1.33-4.36,p < 0.01);2.04 (1.23 ~ 3.37, p < 0.01);2.00 (1.11-3.63, p < 0.001)。结论:中枢性和外周性血压与Sokolow-Lyon心电图电压和肥厚相似。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Blood Pressure 医学-外周血管病

CiteScore

3.00

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： For outstanding coverage of the latest advances in hypertension research, turn to Blood Pressure, a primary source for authoritative and timely information on all aspects of hypertension research and management. Features include: • Physiology and pathophysiology of blood pressure regulation • Primary and secondary hypertension • Cerebrovascular and cardiovascular complications of hypertension • Detection, treatment and follow-up of hypertension • Non pharmacological and pharmacological management • Large outcome trials in hypertension.