Inhibitory Effects and Caspase 3 Activation Activity of Natural Compounds from Anemarrhena Asphodeloides (Bunge) Rhizomes in Vietnam

IF 0.9 Q4 CHEMISTRY, MEDICINAL

Journal of Biologically Active Products from Nature Pub Date : 2021-05-04 DOI:10.1080/22311866.2021.1919207

M. Truong, Mai Lan Huong, N. Anh, S. Shen, P. Khang

引用次数: 0

Abstract

Abstract Three compounds were identified from the ethanolic extract of Anemarrhena asphodeloides Bunge (A. asphodeloides) plant using silica gel chromatography. Their structures were confirmed by NMR and MS data analysis. The inhibitory activities against the MCF7 cancer cell line were evaluated and study the caspase 3 activation activity. Compound 3 exhibited good inhibitory activity and caspase 3 activation activity on the MCF7 cell line.

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越南知母根状茎天然化合物的抑制作用和胱天冬酶3激活活性

摘要采用硅胶色谱法从知母乙醇提取物中分离鉴定出3个化合物。通过核磁共振和质谱数据分析证实了它们的结构。评价其对MCF7癌症细胞系的抑制活性，并研究caspase 3的激活活性。化合物3对MCF7细胞系表现出良好的抑制活性和胱天蛋白酶3激活活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Biologically Active Products from Nature Agricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)

CiteScore

2.10

自引率

0.00%

发文量