A Variant Guillain-Barré Syndrome with Anti-Ganglioside Complex Antibody

Q4 Nursing

Journal of Neurocritical Care Pub Date : 2018-12-27 DOI:10.18700/JNC.180073

S. Huh, So-Young Lee, Jin-Hyung Lee, Won Gu Lee, Jong Kuk Kim, Yoon Bw, Nam Jun Kim

引用次数: 2

Abstract

Background: Recently, anti-ganglioside complex (GSC) antibodies were discovered among the various subtypes of Guillain-Barré syndrome. GSC is the novel glycoepitopes formed by two individual ganglioside molecules. Case Report: We present a 36-year-old man with overlap Miller Fisher syndrome and acute bulbar palsy who had anti-GSC antibody that provided diagnostic robustness. Conclusion: Anti-GSC testing could be considered important in patients who show atypical manifestation with negative antibody reaction against each constituent ganglioside. J Neurocrit Care 2018;11(2):134-136

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具有抗神经节苷复合物抗体的变异型格林-巴勒综合征

背景：近年来，在格林-巴利综合征的各种亚型中发现了抗神经节苷脂复合物（GSC）抗体。GSC是由两个单独的神经节苷脂分子形成的新的糖表位。病例报告：我们报告一名36岁的男性，患有重叠Miller Fisher综合征和急性球麻痹，他具有抗GSC抗体，可提供强有力的诊断。结论：抗GSC检测对表现不典型且对神经节苷脂各成分抗体反应阴性的患者具有重要意义。《神经细胞压积护理杂志》2018；11（2）：134-136

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