CHANGES IN THE TREATMENT PLANS OF GLAUCOMA PATIENTS IN A REAL-WORLD SITUATION

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Muhammad Sadiq, Y. J. Mahsood, Waqar Ahmad, M. Khan, Farah Akhtar
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Abstract

OBJECTIVE: To determine the changes in glaucoma prescriptions during a single visit in real-world situation at Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan. METHODS: This cross-sectional descriptive study was conducted at Glaucoma Department of Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan from September 1st, 2015 to February 29th, 2016 after the ethical approval. Of total 876 consecutive participants, 868 were included in the study. Complete ocular examination was carried out for each subject including intraocular pressure (IOP) by Goldmann, visual field and nerve fiber analysis if it was scheduled. Ocular and systemic co-morbidities as well as ocular surgeries were also noted. Number of topical medications including anti-glaucoma and other drugs were recorded before and after their visit. The changes in anti-glaucoma medications were then categorized as unchanged, changed, added or deleted. The results were analyzed via SPSS version-24. RESULTS: A total 1600 eyes of 868 patients were included in this study. Out of 868 patients, 507 (58.41%) were males and 291 (33.52%) were in 61-70 years age group. Majority of patients (n=680/868: 78.34%) had open-angle glaucoma. Out of 1600 eyes studied, 574 (35.87%) had moderate and 556 (34.75%) had severe stage of glaucomatous optic neuropathy. During single visit, glaucoma-related prescriptions were unchanged, changed, added and deleted in 618/868 (71.20%), 84/868 (9.68%), 95/868 (10.94%) & 71/868 (8.18%) patients respectively. In our study, 911/1600 (56.94%) eyes achieved target IOP ≤14 mmHg. CONCLUSION: In real-world situation, most of our glaucoma patients were stable and required no changes to their prescriptions in single visit.
青光眼患者治疗方案在现实世界中的变化
目的:了解巴基斯坦拉瓦尔品第Al-Shifa信托眼科医院一次就诊中青光眼处方的变化情况。方法:本横断面描述性研究于2015年9月1日至2016年2月29日在巴基斯坦拉瓦尔品第Al-Shifa信托眼科医院青光眼科进行,经伦理批准。在总共876名连续参与者中,有868人被纳入研究。对每位受试者进行完整的眼部检查,包括Goldmann眼压(IOP)、视野和神经纤维分析(如有安排)。眼部和全身合并症以及眼部手术也被注意到。记录患者就诊前后的局部用药数量,包括抗青光眼药物和其他药物。然后将抗青光眼药物的变化分为不变、改变、增加或删除。结果通过SPSS version-24进行分析。结果:本研究共纳入868例患者1600只眼。868例患者中,男性507例(58.41%),61 ~ 70岁291例(33.52%)。多数患者为开角型青光眼(n=680/868: 78.34%)。在1600只眼中,574只(35.87%)为中度青光眼视神经病变,556只(34.75%)为重度青光眼视神经病变。单次访视中,618/868(71.20%)、84/868(9.68%)、95/868(10.94%)和71/868(8.18%)患者青光眼相关处方不变、更改、增加和删除。在我们的研究中,911/1600(56.94%)的眼睛达到了IOP≤14 mmHg的目标。结论:在实际情况下,大多数青光眼患者病情稳定,无需单次更换处方。
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来源期刊
Khyber Medical University Journal-KMUJ
Khyber Medical University Journal-KMUJ MEDICINE, GENERAL & INTERNAL-
CiteScore
0.30
自引率
0.00%
发文量
15
审稿时长
20 weeks
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