The relationship between maternal serum apelin-36 level and anthropometric indices up to 18 months after birth; A cohort Study

IF 0.1 Q4 PEDIATRICS

Acta Pediatrica de Mexico Pub Date : 2022-08-09 DOI:10.18233/apm43no4pp221-2292236

Shiva Pourali Roudbaneh, N. Tehranian, A. Saber, Matin Sadat-Esmaeilzadeh, A. Kazemnejad

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引用次数: 0

Abstract

BACKGROUND & OBJECTIVE: Apelin plays an important role in regulating energy intake and homeostasis. This study aims to investigate the relationship between maternal serum apelin-36 and infants’ anthropometric markers up to 18 months after birth.MATERIAL & METHODS: In this cohort study, 166 pregnant women aged 18-40 years old third trimester period referred to the Prenatal Clinic, participated in this study. The women were divided into two groups: an elective cesarean section group (as an exposure; n = 23), and a vaginal delivery group (as a non-exposure; n = 22). Maternal serum Apelin-36 levels were measured during the third trimester period and after delivery using ELISA. Infants were followed for up to 18 months during the postpartum period.RESULTS: The serum level of Apelin-36 after delivery was significantly and positively correlated with the weight of infants at 12 months, and 18 months P<0.05. It was also correlated with the height of infants at 6 months P<0.05 and 18 months P<0.05. Additionally, Apelin-36 was significantly correlated with the head circumference at 12 months P < 0.05.CONCLUSIONS: The maternal serum Apelin-36 level showed a relationship with the infant’s anthropometric indicators and gender.

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孕妇血清apelin-36水平与出生后18个月人体测量指标的关系；队列研究

背景与目的：Apelin在调节能量摄入和体内平衡方面发挥着重要作用。本研究旨在探讨孕妇血清apelin-36与出生后18个月婴儿的人体测量标志物之间的关系。材料与方法：在这项队列研究中，166名年龄在18-40岁的孕晚期孕妇参加了这项研究。这些妇女被分为两组：选择性剖宫产组（暴露；n=23）和阴道分娩组（非暴露；n=22）。在妊娠晚期和分娩后使用ELISA测量母体血清Apelin-36水平。产后对婴儿进行长达18个月的随访。结果：产后血清Apelin-36水平与12个月和18个月婴儿的体重呈显著正相关，P<0.05。它还与6个月时婴儿的身高相关P＜0.05，与18个月时的婴儿身高相关P＞0.05。此外，Apelin-36与12个月时的头围显著相关，P<0.05。

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来源期刊

Acta Pediatrica de Mexico PEDIATRICS-

CiteScore

0.50

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Acta Pediátrica de México (APM) se publica desde 1980 de manera puntual e ininterrumpida y es el Órgano Oficial del Instituto Nacional de Pediatría. Es una publicación bimestral que tiene como propósito fundamental la difusión de evidencia científica y de información generada como producto de investigación original básica, clínica, epidemiológica y social en el campo de la pediatría, que permita generar y mejorar los modelos de atención a la salud durante la infancia y la adolescencia.