Primary neonatal sacrococcygeal neuroblastoma masquerading as a teratoma: A case report

Q4 Medicine
O. A. Edan, Nazar MT Jawhar
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引用次数: 0

Abstract

Background: Neonatal tumors comprise about 2% of all pediatric malignancies, with neuroblastoma having the highest incidence. Neuroblastoma involving the adrenal medulla and sympathetic ganglia is the most typical scenario in infancy, while the pelvic variant is rare. We report this case because of the unusual and rare presentation of neuroblastoma in a newborn baby mimicking sacrococcygeal teratoma. Case Presentation: A newborn male baby presented with a firm sacral mass, about 5 x 7 cm, with normal overlying skin. MRI revealed an intrapelvic mass extending to the sacral region encasing the coccyx. After preparation, complete tumor excision was performed, and the diagnosis of neuroblastoma was confirmed by histological and immunohistochemical study. Conclusion: Primary neonatal neuroblastoma presenting as a sacrococcygeal mass is a rare and atypical clinical finding of neuroblastoma. It is hard to diagnose this sort of tumor preoperatively unless the mass is subjected to histological and immunohistochemical analysis after tumor excision.
新生儿原发性骶尾骨神经母细胞瘤伪装成畸胎瘤:1例报告
背景:新生儿肿瘤约占所有儿科恶性肿瘤的2%,其中神经母细胞瘤的发病率最高。累及肾上腺髓质和交感神经节的神经母细胞瘤是婴儿期最典型的情况,而盆腔变异则很罕见。我们报告这一病例是因为在一个模仿骶尾部畸胎瘤的新生儿中出现了罕见的神经母细胞瘤。病例介绍:一名新生男婴出现一个约5 x 7厘米的坚固骶骨肿块,其上覆皮肤正常。核磁共振成像显示一个骨盆内肿块延伸到包围尾骨的骶骨区域。准备好后,进行了完整的肿瘤切除,并通过组织学和免疫组织化学研究证实了神经母细胞瘤的诊断。结论:新生儿原发性神经母细胞瘤表现为骶尾部肿块,是一种罕见且非典型的神经母细胞癌临床表现。除非在肿瘤切除后对肿块进行组织学和免疫组织化学分析,否则很难在术前诊断出这种肿瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Neonatal Surgery
Journal of Neonatal Surgery Medicine-Surgery
CiteScore
0.30
自引率
0.00%
发文量
29
审稿时长
6 weeks
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