An unusual occurrence of synchronous gastrointestinal stromal tumor and high-grade serous carcinoma of the endometrium - A rare combination

D. Fonseca, S. Arya, K. Raju
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引用次数: 1

Abstract

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal (GI) tract and comprise <2.2% of all GI tumors. The incidence of endometrial cancer in India is 1.2%. Among synchronous cancers, female genital tract tumors, mostly endometrioid/ovarian carcinomas, constitute 5% of GIST patients. We describe an unusual case with synchronous occurrence of GIST of the stomach with high-grade serous carcinoma (HGSC) of the endometrium, which was proven by histopathological examination and further confirmed by immunohistochemistry. This is the first case published so far of a patient with synchronous occurrence of low-risk GIST of the stomach with HGSC of the endometrium. The main objective of the study is to present a unique case because we have not found any reports for coexistence of the described neoplasm as in our patient, and we hope that it will be valuable in future investigations about the genesis, diagnosis, and treatment of these types of tumors.
罕见的同步性胃肠道间质瘤和子宫内膜高级别浆液性癌的合并
胃肠道间质瘤(gist)是胃肠道最常见的间质肿瘤,占胃肠道肿瘤的2.2%以下。印度子宫内膜癌的发病率为1.2%。在同步肿瘤中,女性生殖道肿瘤,主要是子宫内膜样癌/卵巢癌,占GIST患者的5%。我们报告一例罕见的胃间质间质瘤与子宫内膜高级别浆液性癌(HGSC)同时发生的病例,经组织病理学检查证实,并经免疫组织化学进一步证实。这是迄今为止发表的第一例同时发生低风险胃间质间质瘤和子宫内膜HGSC的患者。本研究的主要目的是提出一个独特的病例,因为我们还没有发现任何报告所描述的肿瘤在我们的患者中共存,我们希望它将对未来研究这些类型的肿瘤的发生、诊断和治疗有价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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