Combination of new coronavirus infection and HIV infection

Q4 Medicine

HIV Infection and Immunosuppressive Disorders Pub Date : 2023-01-24 DOI:10.22328/2077-9828-2022-14-4-41-48

E. A. Belashov, A. Isakov, V. Zinserling

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Abstract

Objective. Evaluation of different options for the formulation of a pathoanatomical diagnosis in the combined course of HIV infection and a new coronavirus infection COVID19Materials and methods. The study included the protocols of clinical autopsies performed at the S. P. Botkin Clinical Infectious Diseases Hospital from March 2020 to September 2021, with the simultaneous diagnosis of HIV infection and the new coronavirus infection COVID19.Results and discussion. Among the secondary diseases in HIV infection in combination with a new coronavirus infection, no significant difference was found in comparison with HIV monoinfection. On the part of the new coronavirus infection, no relationship was found between the course of the infection and the manifestations of secondary diseases in HIV infection. In cases with a protracted new coronavirus infection against the background of a mild HIV infection, the dominant disease in thanatogenesis is COVID-19. In the presence of severe secondary diseases of HIV infection, it acts as the main infection. In cases of the presence of other competing diseases in PAD, they play a leading role in thanatogenesis, or have a significant impact on the course of the disease.Conclusion. Based on the analysis of autopsy protocols with the simultaneous diagnosis of HIV infection and the new coronavirus infection COVID19, various options for the formulation of pathoanatomical diagnosis and encryption of observations are justified

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新型冠状病毒感染合并HIV感染

客观的评估HIV感染和新型冠状病毒感染COVID19联合过程中病理解剖诊断的不同方案材料和方法。该研究包括2020年3月至2021年9月在S.P.Botkin临床传染病医院进行的临床尸检方案，同时诊断为HIV感染和新型冠状病毒感染COVID19。结果和讨论。在HIV感染合并新冠病毒感染的继发性疾病中，与HIV单感染相比没有发现显著差异。在新型冠状病毒感染方面，没有发现感染过程与HIV感染的继发疾病表现之间的关系。在轻度艾滋病毒感染背景下长期感染新冠病毒的病例中，致死的主要疾病是新冠肺炎。在存在严重的艾滋病继发性疾病的情况下，它是主要的感染者。在PAD中存在其他竞争性疾病的情况下，它们在乙醇生成中发挥主导作用，或对疾病的进程产生重大影响。结论基于对同时诊断HIV感染和新型冠状病毒感染COVID19的尸检方案的分析，制定病理解剖诊断和加密观察的各种选择是合理的

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来源期刊

HIV Infection and Immunosuppressive Disorders Medicine-Infectious Diseases

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： In the scientific-practical journal "HIV Infection and Immunosuppressive Disorders", published various issues of HIV medicine (epidemiology, molecular mechanisms of pathogenesis to the development of educational programs) leading scientists of Russia and countries of CIS, USA, as well as practical healthcare professionals working in research centers, research institutes, universities, clinics where done basic medical work. A special place on the pages of the publication is given to basic and clinical research, analytical reviews of contemporary and foreign reports, the provision of medical care for various diseases.