Green synthesis and characterization of zinc oxide nanoparticles using extracts of Artemisia annua l. grown in Togo

Pub Date : 2021-10-01 DOI:10.15251/jobm.2021.134.193
K. Sesime, M. M. Dzagli, K. B. Afoudji
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Abstract

Plant-mediated synthesis of ZnO nanoparticles (ZnONPs) is preferable than the conventional methods with many applications in medicine and biology. Artemisia annua is recognized to have antiplasmodial, antimicrobial activities, so the nanoformulation based on its extracts and zinc oxide would be of therapeutic benefit. This study aims to investigate properties of ZnONPs based on Artemisia annua leaves and stems extracts and zinc acetate. Spectroscopy techniques, XRD, SEM and Energy Dispersive X-ray Spectroscopy (EDS) were used to investigate the structural and optical properties of the ZnONPs. The characteristic absorption peak was at 375.5 nm and the excitation at 365 nm showed wide spectra in visible (450-700 nm). XRD, SEM and EDS analysis confirmed a pure ZnONPs in wurtzite hexagonal structure with a size of 21.34 - 24.71 nm. These nanoformulations would be multifunctional and are candidate for treatment of malaria, cosmetics and optoelectronic.
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利用多哥青蒿提取物绿色合成氧化锌纳米颗粒及其表征
植物介导合成ZnO纳米粒子(ZnONPs)比传统的方法更有优势,在医学和生物学上有许多应用。黄花蒿具有抗疟原虫、抗菌活性,以其提取物和氧化锌为基础的纳米制剂具有良好的治疗效果。本研究以黄花蒿叶茎提取物和乙酸锌为原料,研究其ZnONPs的性质。利用光谱学技术、XRD、SEM和能谱仪(EDS)研究了ZnONPs的结构和光学性质。其特征吸收峰在375.5 nm处,365 nm处激发,可见光谱较宽(450 ~ 700 nm)。XRD、SEM和EDS分析证实了纯ZnONPs为纤锌矿六方结构,尺寸为21.34 ~ 24.71 nm。这些纳米制剂将是多功能的,是治疗疟疾、化妆品和光电子的候选药物。
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