Some Traits on the Outcome of the Treatment of Cervical Cancer in Tanzania: A Case Study of Ocean Road Cancer Institute (ORCI)

Q4 Medicine
Bakari L Leguma, Rajabu Rocky Akarro, A. Msengwa, F. Sichona
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引用次数: 1

Abstract

Background: In Tanzania, like in many other poor African countries, cervical cancer is a major problem facing women especially for those aged 30 years and above. This study aimed at constructing a statistical model to enable the prediction of the outcome of treatment for cervical cancer patients in Tanzania. Methods: Data were collected retrospectively from patient’s files with histological proven cervical cancer who were treated at Ocean Road Cancer Institute (ORCI) from year 2009 and followed up to year 2011. The factors considered are screening status, HIV status, disease stage, age, treatment type and the intent of the treatment. The study employed the Chi-square (χ2) test and the logistic regression model for its analysis. Results:  The Chi-square (χ2) test result showed that there was a significant relationship between outcome of treatment and the patient screening status, HIV status, disease stage and intent of treatment at 5% level of significance. On the other hand, the logistic regression results found patient disease stage and intent of the treatment to be statistically significant at 95 percent. Logistic regression results also showed that patients who attended ORCI when their disease at a late stage had an odds ratio of 0.128 less likely to have favorable outcomes compared to those patients who attended ORCI when their disease stage was at early stages. The odds ratio for cervical cancer patients who received both treatment, radiotherapy, and chemotherapy was 2.643 more likely to have favorable outcomes Conclusion:  More emphasis and campaigns should be made in order to encourage women all over the country to attend cancer centers for screening and treatment at early stages or even before any symptoms for cervical cancer and other types of cancers.
坦桑尼亚癌症宫颈癌治疗结果的一些特点:海洋路癌症研究所(ORCI)的案例研究
背景:在坦桑尼亚,像许多其他贫穷的非洲国家一样,宫颈癌是妇女面临的主要问题,特别是30岁及以上的妇女。本研究旨在建立统计模型,以预测坦桑尼亚宫颈癌患者的治疗结果。方法:回顾性收集2009年至2011年在海洋路癌症研究所(ORCI)接受组织学证实的宫颈癌患者资料。考虑的因素包括筛查状况、艾滋病毒状况、疾病阶段、年龄、治疗类型和治疗意图。本研究采用χ2检验和logistic回归模型进行分析。结果:卡方(χ2)检验结果显示,治疗结果与患者筛查状态、HIV状态、疾病分期和治疗意图之间存在显著相关,在5%的显著水平上。另一方面,逻辑回归结果发现,95%的患者疾病分期和治疗意图具有统计学显著性。Logistic回归结果还显示,在疾病晚期参加ORCI的患者与在疾病早期参加ORCI的患者相比,有0.128的优势比不太可能有良好的结果。同时接受治疗、放疗和化疗的宫颈癌患者的优势比为2.643,更有可能获得良好的结果。结论:为了鼓励全国各地的妇女在宫颈癌和其他类型癌症的早期阶段甚至在出现任何症状之前到癌症中心进行筛查和治疗,应该更加重视和开展宣传活动。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Tanzania Journal of Health Research
Tanzania Journal of Health Research Medicine-Medicine (all)
CiteScore
0.20
自引率
0.00%
发文量
20
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