Detection of mammary adenocarcinoma metastases in a cat through 99mTc-thymine scintigraphy

IF 0.2 4区 农林科学 Q2 Veterinary
Paulo S. Castelo-Branco, Gabriel Gutfilen-Schlesinger, P. Sena, Guile Gutfilen-Schlesinger, Sergio Souza, B. Gutfilen
{"title":"Detection of mammary adenocarcinoma metastases in a cat through 99mTc-thymine scintigraphy","authors":"Paulo S. Castelo-Branco, Gabriel Gutfilen-Schlesinger, P. Sena, Guile Gutfilen-Schlesinger, Sergio Souza, B. Gutfilen","doi":"10.22201/fmvz.24486760e.2020.2.718","DOIUrl":null,"url":null,"abstract":"Mammary adenocarcinomas with metastases are more common in dogs than in cats. Their incidence is 1 in every 4,000 cats. In routine veterinary practice, laboratory exams for diagnosis of these neoplasms are nonspecific and scarcely used. Even though invasive procedure, biopsy, and histopathological findings are the gold standards that define the clinical approach, the clinical evaluation, and image assessment lead the way to the proper treatment, especially when surgical intervention is a possibility. This study describes the clinical signs, histopathological aspects, radiological and scintigraphic findings of a cat with mammary adenocarcinoma and metastases evaluated one hour after intravenous administration of 99mTc-thymine. Our focus was not to discuss the pathological aspects of the disease but the Nuclear Medicine role in metastases detection. Metastases, when lesser than 4mm, could go unnoticed by radiological exams, whereas scintigraphy may detect them. Using 99mTc-thymine scintigraphy, we successfully detected unsuspected metastases in the lungs, liver, and right kidney. Early diagnosis is the key to a better rate of survival due to the given treatment and prognostic. Hence, we strongly recommend the use of 99mTc-thymine scintigraphy as a complementary tool for breast cancer diagnosis in veterinary care.","PeriodicalId":49387,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2000,"publicationDate":"2020-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/fmvz.24486760e.2020.2.718","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinaria Mexico","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.22201/fmvz.24486760e.2020.2.718","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Veterinary","Score":null,"Total":0}
引用次数: 1

Abstract

Mammary adenocarcinomas with metastases are more common in dogs than in cats. Their incidence is 1 in every 4,000 cats. In routine veterinary practice, laboratory exams for diagnosis of these neoplasms are nonspecific and scarcely used. Even though invasive procedure, biopsy, and histopathological findings are the gold standards that define the clinical approach, the clinical evaluation, and image assessment lead the way to the proper treatment, especially when surgical intervention is a possibility. This study describes the clinical signs, histopathological aspects, radiological and scintigraphic findings of a cat with mammary adenocarcinoma and metastases evaluated one hour after intravenous administration of 99mTc-thymine. Our focus was not to discuss the pathological aspects of the disease but the Nuclear Medicine role in metastases detection. Metastases, when lesser than 4mm, could go unnoticed by radiological exams, whereas scintigraphy may detect them. Using 99mTc-thymine scintigraphy, we successfully detected unsuspected metastases in the lungs, liver, and right kidney. Early diagnosis is the key to a better rate of survival due to the given treatment and prognostic. Hence, we strongly recommend the use of 99mTc-thymine scintigraphy as a complementary tool for breast cancer diagnosis in veterinary care.
用99mtc胸腺嘧啶显像检测猫乳腺腺癌转移
转移的乳腺腺癌在狗身上比在猫身上更常见。它们的发病率为每4000只猫中就有1只。在常规兽医实践中,诊断这些肿瘤的实验室检查是非特异性的,很少使用。尽管侵入性手术、活检和组织病理学检查结果是定义临床方法的金标准,但临床评估和图像评估为正确治疗指明了道路,尤其是在可能进行手术干预的情况下。本研究描述了一只猫在静脉注射99mTc-胸腺嘧啶一小时后评估的乳腺腺癌和转移的临床症状、组织病理学方面、放射学和闪烁扫描结果。我们的重点不是讨论该疾病的病理方面,而是讨论核医学在转移瘤检测中的作用。当转移瘤小于4毫米时,放射学检查可能不会注意到,而闪烁扫描可能会检测到。使用99mTc-胸腺嘧啶闪烁显像,我们成功地检测到肺、肝和右肾中未被怀疑的转移。由于给定的治疗和预后,早期诊断是提高生存率的关键。因此,我们强烈建议在兽医护理中使用99mTc-胸腺嘧啶闪烁显像作为乳腺癌症诊断的补充工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Veterinaria Mexico
Veterinaria Mexico VETERINARY SCIENCES-
自引率
0.00%
发文量
0
审稿时长
>12 weeks
期刊介绍: Veterinaria México OA (ISSN 2448-6760) is an online scientific journal edited by Universidad Nacional Autónoma de México (UNAM). The journal is Open Access and follows UNAM''s initiative, to transmit knowledge free of charge to the readership and authors, with no Article Processing Charges. This journal publishes advances in Veterinary Sciences and Animal Production, and to reach more lectures across the world the journal was updated since 2014 from its predecessor printed in paper Veterinaria México (ISSN 0301-5092) and its digital version (ISSN 2007-5472).
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信