Tumors of Oligodendroglial Origin, Results of a Five-Year Study

Abstract

Objective: Oligodendrogliomas are intracranial tumors that represent between 5 to 25 % of gliomas in adults. This study reviews the results of treatment in patients with oligodendrogliomas treated at “Hermanos Ameijeiras” Hospital between January 2015 and December 2020. Methods: We made an observational, descriptive and retrospective study type cohort in a series of 31 patients with oligodendroglioma treated at “Hermanos Ameijeiras” Hospital. Results: Predominate male patients with ages between 41 to 60 years (55%), with clinical presentation of seizures in 71% and frontal location in 52%. Total surgical resection was performed in 84% of patient, which supported by adjunctive treatment, achieved total regression of disease in 71 % of patients and postoperative improvement in 100% of the patients according to the Karnofsky functional scale. Conclusions: Oligodendroglia tumors are gliomas with their own imaging, histological and genetic characteristics. Combination of the different therapeutic modalities has an important role in the control of the disease and its survival, associated with a better neurofunctional state of the patient in the pre-surgical and post-surgical period