Impact of heat stress length and dietary antioxidant supplementation on the nutrient digestibility, metabolism and immune response of fattening pigs

IF 3.5 2区 农林科学 Q1 AGRICULTURE, MULTIDISCIPLINARY
Arth David Sol Valmoria Ortega , László Babinszky , Ogonji Humphrey Oriedo , Brigitta Csernus , Xénia Erika Ozsváth , Levente Czeglédi , János Oláh , Csaba Szabó
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引用次数: 0

Abstract

Study aimed to investigate the impact of long-term high ambient temperature (HAT) exposure and dietary antioxidant supplementation (elevated levels and in combination) on nutrient digestibility, metabolism and immune response of pigs. A total of 36 Danbred barrows (65.1 ± 2.81 kg) were allotted to four treatments: Trm1: HAT (28.9 ± 0.9 °C) + control diet (CD); Trm2: HAT + elevated vitamin C and E and Se and Zn; Trm3: HAT + further elevated vitamin C and E and Se and Zn; and Trm4: thermo-neutral ambient temperature (19.5 ± 0.9 °C) + CD. Nutrients (DM, CP, Cfat, CF, CA, GE) and minerals (Ca, P, Na, Zn, Se) digestibility were determined. Plasma metabolite and cytokine concentrations were investigated from the blood samples collected on d 15 and 28. Heat shock proteins (HSP 70 and 90) and tumor necrosis factor-alpha (TNF-α) expressions were investigated from jejunum samples of pigs. HAT did not significantly affect pigs' nutrient digestibility and retention (P > 0.05). However, Trm2 pigs had greater digestibility in terms of DM, CF, Ca, Zn, Se and retention of Ca, Zn, Na, and Se than Trm1 and Trm4 groups. Trm3 pigs had significantly higher (P < 0.05) creatinine concentrations than Trm4 pigs. HAT did not significantly affect the expression of cytokines; however, vitamins and micro-minerals supplementation in the diet significantly (P < 0.05) improved interleukin (IL) 10 expression, reduced TNF-α, and HSP70 expressions. Vitamin and micro-mineral fortified diet can improve pigs' nutrient and mineral digestibility and could alleviate inflammatory response in pigs exposed to HAT.

热应激时间和日粮添加抗氧化剂对育肥猪营养物质消化、代谢和免疫反应的影响
本研究旨在探讨长期高温环境和饲粮中添加抗氧化剂(高水平或联合添加)对猪营养物质消化率、代谢和免疫反应的影响。选取36头丹种犊牛(体重65.1±2.81 kg),分为4个处理:Trm1: HAT(28.9±0.9°C) +对照饲粮(CD);Trm2: HAT +维生素C、E、Se、Zn升高;Trm3: HAT +进一步升高维生素C、E、Se、Zn;Trm4:热中性环境温度(19.5±0.9°C) + CD。测定营养物质(DM、CP、Cfat、CF、CA、GE)和矿物质(CA、P、Na、Zn、Se)消化率。在第15天和第28天采集血液样本,检测血浆代谢物和细胞因子浓度。研究了猪空肠样品热休克蛋白(hsp70和90)和肿瘤坏死因子-α (TNF-α)的表达。HAT对猪的营养物质消化率和滞留率无显著影响(P >0.05)。而Trm2组DM、CF、Ca、Zn、Se的消化率和Ca、Zn、Na、Se的保留率均高于Trm1和Trm4组。Trm3猪的P <0.05)肌酐浓度高于Trm4猪。HAT对细胞因子的表达无显著影响;然而,饮食中维生素和微量矿物质的补充显著(P <0.05)提高白细胞介素(IL) 10的表达,降低TNF-α和HSP70的表达。维生素和微量矿物质强化饲粮可提高猪的营养和矿物质消化率,并可减轻HAT暴露猪的炎症反应。
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来源期刊
Annals of Agricultural Science
Annals of Agricultural Science AGRICULTURE, MULTIDISCIPLINARY-
CiteScore
12.60
自引率
0.00%
发文量
18
审稿时长
33 days
期刊介绍: Annals of Agricultural Sciences (AOAS) is the official journal of Faculty of Agriculture, Ain Shams University. AOAS is an open access peer-reviewed journal publishing original research articles and review articles on experimental and modelling research at laboratory, field, farm, landscape, and industrial levels. AOAS aims to maximize the quality of the agricultural sector across the globe with emphasis on the Arabian countries by focusing on publishing the high-quality applicable researches, in addition to the new methods and frontiers leading to maximizing the quality and quantity of both plant and animal yield and final products.
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