Bone mineral density radiopaque templates for cone beam computed tomography and multidetector computed tomography

Digital Diagnostics Pub Date : 2023-08-30 DOI:10.17816/dd501771

S. J. Hossain, A. Petraikin, A. Muraev, A. Danaev, D. Burenchev, A. Dolgalev, Y. Vasilev, Darya E. Sharova, Andrey Yu. Tikhmyanov, Sergey Y. Ivanov

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引用次数: 0

Abstract

Background: Cone beam computed tomography (CBCT) applied for diagnostics and planning various manipulations in the maxillofacial region, e.g. dental implantation. The advantages of this method are high spatial resolution, low radiation exposure, low cost. However, it has a significant drawback: the inability to determine the density of the jaw bone in Hounsfield Units (HU). Aims: To develop radiopaque templates with sets of X-ray density based on potassium hydrophosphate (PHP) and beta-tricalcium phosphate (betta-TCP), to study templates on various CBCT and multidetector computed tomography (MDCT) devices and to determine a cross-calibration algorithm for assessing the bone mineral density (BMD) of the jaw in HU. Materials and methods: BMD template consists microtubes (0.25 ml), PHP concentrations were set: 49.96; 99.98; 174.99; 349.99; 549.98 mg/ml, as well as a suspension of betta-TCP with an equivalent concentration of PHP 1506 mg/ml: simulate the types of bone density according to C.Mish. The study was carried out on 2 MDCT and 4 CBCT. Cross-calibration was referred on the "standard" MDCT1 mode 120 kV, 200 mA. Results: There was a significant scatter of the X-ray values (HU for MDCT and GV for CBCT) vs BMD; the slopes, bias and the shapes of the curves was differing. After cross-calibration, good comparability corresponding to the MDCT1 mode was shown. The median of the differences before cross-calibration was 160 relative units (HU, GV); after decreased by 10 times and amounted to 16 rel. units (p=0.000). The mean difference for CBCT was significantly higher (30 rel. units) than for MDCT (8 rel. units), p=0.024 Mann-Whitney test. Conclusions: The developed radiopaque template makes it possible to standardize densitometric indicators for CBCT and various MSCT modes, on average, the spread after cross-calibration is reduced by 10 times, which makes it possible to classify bone tissue in HU according to C. Mish.

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锥形束计算机断层扫描和多探测器计算机断层扫描的骨矿物质密度不透射线模板

背景：锥束计算机断层扫描（CBCT）应用于颌面部的诊断和规划各种操作，如牙齿植入。该方法的优点是空间分辨率高、辐射量小、成本低。然而，它有一个显著的缺点：无法确定Hounsfield单位（HU）的颌骨密度。目的：开发基于磷酸氢钾（PHP）和β-磷酸三钙（betta TCP）的X射线密度不透射线模板，研究各种CBCT和多探测器计算机断层扫描（MDCT）设备上的模板，并确定用于评估HU颌骨骨密度（BMD）的交叉校准算法。材料和方法：骨密度模板由微管（0.25ml）组成，设定PHP浓度：49.96；99.98；174.99；349.99；549.98 mg/ml，以及等效浓度为PHP 1506 mg/ml的斗鱼TCP悬浮液：根据C.Mish模拟骨密度类型。该研究在2个MDCT和4个CBCT上进行。交叉校准参考“标准”MDCT1模式120 kV，200 mA。结果：X射线值（MDCT为HU，CBCT为GV）与BMD之间存在显著的散射；曲线的斜率、偏差和形状各不相同。交叉校准后，显示出与MDCT1模式相对应的良好可比性。交叉校准前差异的中位数为160个相对单位（HU，GV）；CBCT的平均差异（30个rel.单位）显著高于MDCT的平均差（8个rel.单元），p=0.024 Mann-Whitney检验。结论：所开发的不透射线模板使CBCT和各种MSCT模式的密度计指标标准化成为可能，平均而言，交叉校准后的扩散减少了10倍，这使根据C.Mish对HU中的骨组织进行分类成为可能。

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来源期刊

Digital Diagnostics

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

5 weeks