Research progress in hemolytic disease in fetuses and newborns: a review

Q4 Medicine

中华围产医学杂志 Pub Date : 2020-01-16 DOI:10.3760/CMA.J.ISSN.1007-9408.2020.01.009

Yuanjun Wu, Fubing Yu, Yong Yang

引用次数: 0

Abstract

Hemolytic disease in fetuses and newborns (HDFN) is a common perinatal condition caused by the destruction of erythrocytes of neonates or fetuses by maternal IgG antibodies. Fetal or neonatal hemolysis is HDFN's primary pathological process resulting in anemia and neonatal jaundice. This review summarized recent progress in the pathophysiology of HDFN, the clinical correlation between anti-erythrocyte alloantibodies and HDFN, laboratory tests for alloimmunization in pregnancy, clinical evaluation of high-risk cases of HDFN, and treatment and prevention of HDFN at home and abroad. Key words: Erythroblastosis, fetal; Rh Isoimmunization; Immunoglobulin G; Isoantibodies

查看原文本刊更多论文

胎儿和新生儿溶血性疾病的研究进展

胎儿和新生儿溶血病(hddn)是一种常见的围产期疾病，由母体IgG抗体破坏新生儿或胎儿的红细胞引起。胎儿或新生儿溶血是HDFN的主要病理过程，导致贫血和新生儿黄疸。本文综述了HDFN的病理生理、抗红细胞同种异体抗体与HDFN的临床相关性、妊娠期同种异体免疫的实验室检测、HDFN高危病例的临床评价、国内外HDFN的治疗和预防等方面的最新进展。关键词:红细胞增多症;胎儿;Rh同种免疫接种;免疫球蛋白G;同族抗体

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

中华围产医学杂志 Medicine-Obstetrics and Gynecology

CiteScore

0.70

自引率

0.00%

发文量

4446

期刊介绍： Chinese Journal of Perinatal Medicine was founded in May 1998. It is one of the journals of the Chinese Medical Association, which is supervised by the China Association for Science and Technology, sponsored by the Chinese Medical Association, and hosted by Peking University First Hospital. Perinatal medicine is a new discipline jointly studied by obstetrics and neonatology. The purpose of this journal is to "prenatal and postnatal care, improve the quality of the newborn population, and ensure the safety and health of mothers and infants". It reflects the new theories, new technologies, and new progress in perinatal medicine in related disciplines such as basic, clinical and preventive medicine, genetics, and sociology. It aims to provide a window and platform for academic exchanges, information transmission, and understanding of the development trends of domestic and foreign perinatal medicine for the majority of perinatal medicine workers in my country.