From society to cells and back again: new opportunities for discovery at the biosocial interface.

Discover Social Science and Health Pub Date : 2022-01-01 Epub Date: 2022-03-09 DOI:10.1007/s44155-022-00007-z

Thomas W McDade, Kathleen Mullan Harris

引用次数: 0

Abstract

A new generation of community- and population-based research is combining measures of social context, experience, and behavior with direct measures of physiology, gene sequence and function, and health. Studies drawing on models and methods from the social and biological sciences have the potential to illuminate the multilevel mechanisms through which experience becomes biology, and to move past decontextualized and reductionistic approaches to human development, behavior, and health. In this perspective we highlight challenges and opportunities at the biosocial interface, and briefly discuss COVID-19 as a case study demonstrating the importance of linking across levels of analysis.

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从社会到细胞再回来:在生物社会界面上发现的新机会

新一代以社区和人口为基础的研究正在将社会背景、经验和行为的测量方法与生理、基因序列和功能以及健康的直接测量方法结合起来。利用社会科学和生物科学的模型和方法进行的研究有可能揭示经验转化为生物学的多层次机制，并超越对人类发展、行为和健康的非情境化和还原论方法。在这一视角中，我们强调了生物-社会界面的挑战和机遇，并简要讨论了 COVID-19 这一案例研究，它展示了跨分析层面联系的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Discover Social Science and Health intersection of health and social sciences-

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

22 days

期刊介绍： Discover Social Science and Health is an interdisciplinary, international journal that publishes papers at the intersection of the social and biomedical sciences. Papers should integrate, in both theory and measures, a social perspective (reflecting anthropology, criminology, economics, epidemiology, policy, sociology, etc) and a concern for health (mental and physical). Health, broadly construed, includes biological and other indicators of overall health, symptoms, diseases, diagnoses, treatments, treatment adherence, and related concerns. Drawing on diverse, sound methodologies, submissions may include reports of new empirical findings (including important null findings) and replications, reviews and perspectives that construe prior research and discuss future research agendas, methodological research (including the evaluation of measures, samples, and modeling strategies), and short or long commentaries on topics of wide interest. All submissions should include statements of significance with respect to health and future research. Discover Social Science and Health is an Open Access journal that supports the pre-registration of studies. Topics Papers suitable for Discover Social Science and Health will include both social and biomedical theory and data. Illustrative examples of themes include race/ethnicity, sex/gender, socioeconomic, geographic, and other social disparities in health; migration and health; spatial distribution of risk factors and access to healthcare; health and social relationships; interactional processes in healthcare, treatments, and outcomes; life course patterns of health and treatment regimens; cross-national patterns in health and health policies; characteristics of communities and neighborhoods and health; social networks and treatment adherence; stigma and disease progression; methodological studies including psychometric properties of measures frequently used in health research; and commentary and analysis of key concepts, theories, and methods in studies of social science and biomedicine. The journal welcomes submissions that draw on biomarkers of health, genetically-informed and neuroimaging data, psychophysiological measures, and other forms of data that describe physical and mental health, access to health care, treatment, and related constructs.