Bronchoscopic Assessment of Radiologically Detected Lung Lesion

Monjurul Kader Chowdhury, Palas Biswas, P. Sarker, Md Saidur Rahman, Tanzina Begum Chowdhury, Md Masudur Rahman, Khan Abul Kalam Azad
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Abstract

Background: Radiologically detected lung lesions are very common in regular clinical practice. It is very important to diagnose radiologically detected lung lesions early. Flexible fiber-optic bronchoscopy is an excellent minimally invasive and safe investigation for early diagnosis of lung diseases. Methods: Data were collected using a semi-structured questionnaire from the patients who had lesion on chest x-ray that were not in the peripheral part and advised for bronchoscopy. Patients were followed up after getting their histopathology. Statistical analysis using SPSS16.0 was carried out thereafter. Results: Mean age of the respondents was 56.8 years with age ranging from 25 to 85 years. 82% of the patients were male. Male-female ratio was 4.5:1. Endobronchial growth was found in maximum 46% patients during bronchoscopy, followed by 22% showing inflammatory lesion. In 20% of the patients, bronchoscopy findings showed normal findings and 12% patients showed inconclusive results. In subsequent biopsy and histopathology, maximum 55.88% showed non-neoplastic lesion. Among the non-neoplastic lesions 26.47% showed non-specific inflammation.20.58% showed tuberculosis, 5.88% showed sarcoidosis and 2.94% showed aspergilloma. 35.29% cases showed neoplastic lesion, 2.94% showed inconclusive results, 2.94% showed normal results and 2.94% showed inadequate sample. 58.33% cases were squamous cell carcinoma, 25% cases were adenocarcinoma, 8.33% showed small cell carcinoma and 8.33% showed mixed cell type of carcinoma. Conclusion: Fiberoptic bronchoscopy can be successfully employed for the diagnosis of lung diseases, including malignancies and granulomatous lesions.It is extremely useful in finding specific etiologies of various lung diseases. J MEDICINE 2023; 24(2): 106-111
支气管镜下影像学检查肺部病变的评估
背景:在常规临床实践中,放射学检测到的肺部病变是非常常见的。早期影像学诊断肺部病变是非常重要的。柔性纤维支气管镜检查是一种极好的微创、安全的肺部疾病早期诊断方法。方法:采用半结构化问卷收集胸片病变非外周部分并建议行支气管镜检查的患者的资料。在完成组织病理学检查后,对患者进行随访。之后使用SPSS16.0进行统计分析。结果:调查对象平均年龄56.8岁,年龄在25 ~ 85岁之间。82%的患者为男性。男女比例为4.5:1。在支气管镜检查中发现支气管内生长的患者最多46%,其次是22%的炎症病变。在20%的患者中,支气管镜检查结果显示正常,12%的患者结果不确定。在随后的活检和组织病理学中,非肿瘤性病变最多55.88%。非肿瘤性病变中,非特异性炎症占26.47%,结核占20.58%,结节病占5.88%,曲菌肿占2.94%。35.29%为肿瘤病变,2.94%为结果不确定,2.94%为结果正常,2.94%为样本不充分。58.33%为鳞状细胞癌,25%为腺癌,8.33%为小细胞癌,8.33%为混合细胞癌。结论:纤维支气管镜检查可成功诊断肺部疾病,包括恶性肿瘤和肉芽肿性病变。它在寻找各种肺部疾病的具体病因方面非常有用。[J]中华医学杂志2023;24 (2): 106 - 111
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