Audit of patients of the pain clinic of the University Hospital of Heraklion with neuropathic pain during the period 2019–2020

IF 1 4区医学 Q3 EMERGENCY MEDICINE

Signa Vitae Pub Date : 2021-09-15 DOI:10.22514/sv.2021.158

E. Koutoulaki, Amalia Mathioudaki, V. Nyktari, G. Stefanakis, P. Vasilos, S. Ilia, G. Frantzeskos, A. Papaioannou

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引用次数: 1

Abstract

Introduction: Neuropathic pain is caused by a lesion or disease of the somatosensory system and affects 7–10% of the population [1–3]. The aim of this study was the analysis of patients referred with neuropathic pain to the University Hospital of Heraklion pain clinic (2019–2020) in terms of characteristics, underlying disease, treatment and response to treatment. Methods: Patients diagnosed with neuropathic pain (Pain Detect questionnaire) were recruited. Pain intensity was assessed using NAS. Data were in the form of qualitative or quantitative variables and were expressed as frequencies and % frequencies. The x2 test was used to detect statistically significant differences in percentages or correlations between the categorical variables. Statistical analysis was performed using IBM SPSS Statistics 26.0 (IBM Corp., Chicago, IL, USA). Acceptance limit was set to α = 0.05. Results: 120 patients (age 64.0 ± 15.1 years, men 55.8%, cancer history 50%) were included. Merely neuropathic pain occurred in 43.3% of patients. Patients were allocated into two groups: benign pain group —with herpes zoster (23%) and spine diseases (14%) as the most frequent causes—and malignant pain group (mainly due to gynaecological, breast or lung cancer). The groups did not differ in the main symptoms—burning (46.7%), allodynia (23.3%), hyperalgesia (28.3%)—nor in the pain location (most often in lower extremities and pelvis). Both groups experienced sleep disorders—poorer sleep quality in malignant pain (36.7% vs 16.7%)—and poor psychological state (33.9% in benign, 28.8% in malignant pain). NSAIDs use was more common in benign (58.3% vs 15.9%, p 30% following initial treatment and a corresponding reduction in further modification. Conclusions: Most patients with neuropathic pain were >50 years old, reported a burning sensation and experienced effects on quality of life (quality of sleep, psychological state).

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对2019年至2020年期间伊拉克利翁大学医院疼痛诊所神经性疼痛患者的审计

引言：神经性疼痛是由体感系统的损伤或疾病引起的，影响7-10%的人群[1-3]。本研究的目的是分析被转诊至伊拉克利翁大学医院疼痛诊所（2019-2020）的神经性疼痛患者的特征、潜在疾病、治疗和治疗反应。方法：招募被诊断为神经性疼痛的患者（疼痛检测问卷）。使用NAS评估疼痛强度。数据采用定性或定量变量的形式，用频率和%频率表示。x2检验用于检测分类变量之间百分比或相关性的统计学显著差异。使用IBM SPSS Statistics 26.0（IBM Corp.，Chicago，IL，USA）进行统计分析。验收限值设置为α=0.05。结果：纳入120例患者（年龄64.0±15.1岁，男性55.8%，癌症病史50%）。43.3%的患者仅发生神经性疼痛。患者分为两组：良性疼痛组-带状疱疹（23%）和脊柱疾病（14%）是最常见的原因-和恶性疼痛组（主要是由于妇科、乳腺癌或肺癌癌症）。两组在主要症状（烧伤（46.7%）、异常性疼痛（23.3%）、痛觉过敏（28.3%））和疼痛部位（最常见的是下肢和骨盆）方面没有差异。两组患者都有睡眠障碍——恶性疼痛的睡眠质量较差（36.7%对16.7%）——心理状态较差（良性疼痛为33.9%，恶性疼痛为28.8%）。非甾体抗炎药的使用在良性疾病中更为常见（58.3%vs 15.9%，在初次治疗后p 30%，进一步治疗后相应减少。结论：大多数神经性疼痛患者年龄＞50岁，有烧灼感，生活质量（睡眠质量、心理状态）受到影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Signa Vitae 医学-急救医学

CiteScore

1.30

自引率

9.10%

发文量

审稿时长

3 months

期刊介绍： Signa Vitae is a completely open-access，peer-reviewed journal dedicate to deliver the leading edge research in anaesthesia, intensive care and emergency medicine to publics. The journal’s intention is to be practice-oriented, so we focus on the clinical practice and fundamental understanding of adult, pediatric and neonatal intensive care, as well as anesthesia and emergency medicine. Although Signa Vitae is primarily a clinical journal, we welcome submissions of basic science papers if the authors can demonstrate their clinical relevance. The Signa Vitae journal encourages scientists and academicians all around the world to share their original writings in the form of original research, review, mini-review, systematic review, short communication, case report, letter to the editor, commentary, rapid report, news and views, as well as meeting report. Full texts of all published articles, can be downloaded for free from our web site.