Acute kidney injury as a predictor of hospital discharge in COVID-19 patients

Abstract

Background: Since the beginning of the pandemic caused by the SARS-CoV-2 virus, risk factors have been identified. These can lead to complications in patients with comorbidities, acute renal injury is one of the most important complications of COVID-19. Objective: To identify a possible relationship between the indicators of the patient's renal status upon admission and the outcome. Materials and Methods: An observational study (retrospective cohort) of patients (series of confirmed cases of COVID-19) who were admitted to the Hospital Central del Estado de Chihuahua, Mexico, from April 1stto October 20th, 2020. A binary logistic regression model was performed. Results: There were included 266 patients. It was found that 82% did not present acute kidney injury on admission, 11.7% were in stage AKIN I, 13.5% AKIN II and 4.5% AKIN III. Patients with COVID-19 without acute renal injury had a higher probability of hospital discharge than those who developed acute renal injury. Conclusions: Kidney injury influences the prognosis of patients with COVID-19;patients out of range of acute kidney injury based on basal serum creatinine have more probability of being discharged by clinical improvement.