INVITED ARTICLE FROM THE 2020 TEXAS ACADEMY OF SCIENCE TEXAS DISTINGUISHED SCIENTIST

Q4 Agricultural and Biological Sciences

The Texas Journal of Science Pub Date : 2020-01-01 DOI:10.32011/txjsci_72_1_tds

George Perry

引用次数: 0

Abstract

and was the first to discover that oxidative stress is a key feature of this and related neurodegenerative diseases. His studies identified oxidative damage, its source from metabolic/ mitochondria failure and catalysis by iron and copper. This work led to a novel interpretation of the role of amyloid—that instead of causing Alzheimer’s disease, it is a protective antioxidant response, and the reason all the amyloid-based therapies have failed.

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特邀文章来自2020年德州科学院德州杰出科学家

并且是第一个发现氧化应激是这种和相关神经退行性疾病的关键特征的人。他的研究确定了氧化损伤，其来源于代谢/线粒体衰竭以及铁和铜的催化作用。这项工作对淀粉样蛋白的作用做出了新的解释——淀粉样蛋白不是引起阿尔茨海默病，而是一种保护性的抗氧化反应，也是所有基于淀粉样蛋白治疗失败的原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

The Texas Journal of Science Agricultural and Biological Sciences-Ecology, Evolution, Behavior and Systematics

CiteScore

0.50

自引率

0.00%

发文量

期刊介绍： Scholarly manuscripts reporting original research results in any field of science or technology, including science education, will be considered for publication in The Texas Journal of Science. Prior to acceptance, each manuscript will be reviewed by both knowledgeable peers and the editorial staff. Authors are encouraged to suggest the names and addresses of two potential reviewers to the Manuscript Editor at the time of submission of their manuscript.