Comparison of Mineral Trioxide Aggregate and Biodentine for Open Apex Management in Children with Nonvital Immature Permanent Teeth: A Systematic Review

Q4 Dentistry

European Journal of General Dentistry Pub Date : 2022-09-29 DOI:10.1055/s-0042-1750090

V. Ravindran, G. Jeevanandan, Madhulaxmi Marimuthu, Suman Panda, Ather Ahmed Syed, S. Vishwanathaiah, S. Khanagar, Prabhadevi C. Maganur

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引用次数: 2

Abstract

Tricalcium silicate cements have long been used in dentistry for management of open apex. Biodentine was introduced to overcome the disadvantages of mineral trioxide aggregate (MTA). The aim of this systematic review was to compare the success rates of biodentine and MTA as a material of choice for the management of open apex in children with nonvital immature permanent teeth. PubMed/Medline, Scopus, EMBASE, Cochrane, and Google Scholar were searched until November 30, 2021, with the search terms young permanent teeth, immature permanent teeth, open apex, MTA, and biodentine. Based on the inclusion criteria, the articles were selected following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and assessed for quality using a risk-of-bias assessment tool. The outcomes of the studies were qualitatively synthesized. A total of 379 studies were identified and after refinement only two studies met the eligibility criteria. Both the studies were performed in children with nonvital pulp status. One of the studies showed a clinical success of 91.66% for MTA and 100% for biodentine in revascularization cases while the other study showed 100% for both the materials in apexification cases. Radiographic success was 100% for both the materials at the end of the follow-up period in both the studies. Treatment modality can create heterogeneity that does not allow making a pooled conclusion for the two materials collectively, which is the case in this review where one study used revascularization, while the other used apexification. An overall high risk of bias was noticed for the selected studies. With high risk of bias and low quality of evidence, a strong definitive conclusion cannot be arrived at. Further studies with proper randomization and minimal risk of bias are required to provide a conclusive result. However, as per the included studies, biodentine can be a material of choice for revascularization while both MTA and biodentine can be used for apexification procedures.

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矿物三氧化物聚集体和生物牙本质在儿童非生命性未成熟恒牙开放性根尖管理中的比较：系统评价

硅酸三钙胶结剂长期应用于牙科治疗开尖。为了克服矿物三氧化物骨料(MTA)的缺点，引入了生物钛矿。本系统综述的目的是比较生物牙定和MTA作为治疗儿童非生命未成熟恒牙开尖的选择材料的成功率。PubMed/Medline、Scopus、EMBASE、Cochrane和谷歌Scholar检索到2021年11月30日，检索词为young恒牙、immature恒牙、open apex、MTA和biodentine。根据纳入标准，按照系统评价和荟萃分析指南的首选报告项目选择文章，并使用偏倚风险评估工具评估质量。对研究结果进行定性综合。共有379项研究被确定，经过改进后，只有两项研究符合资格标准。这两项研究都是在无牙髓状态的儿童中进行的。其中一项研究显示MTA在血运重建术中的临床成功率为91.66%，生物牙定在血运重建术中的临床成功率为100%，而另一项研究显示两种材料在根尖手术中的临床成功率均为100%。在两项研究的随访期结束时，两种材料的放射照相成功率均为100%。治疗方式可能产生异质性，无法对两种材料共同得出汇总结论，在本综述中，一项研究使用血运重建术，而另一项研究使用根尖化。在所选研究中发现总体偏倚风险较高。由于偏倚风险高，证据质量低，因此无法得出强有力的明确结论。进一步的研究需要适当的随机化和最小的偏倚风险来提供一个结论性的结果。然而，根据纳入的研究，生物牙牙定可以作为血运重建的选择材料，而MTA和生物牙牙定都可以用于根尖手术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of General Dentistry Dentistry-Dentistry (all)

CiteScore

1.00

自引率

0.00%

发文量

期刊介绍： European Journal of General Dentistry (EJGD) is one of the leading open-access international dental journal within the field of Dentistry. The aim of EJGD is publishing novel and high-quality research papers, as well as to influence the practice of dentistry at clinician, research, industry and policy-maker level on an international basis. EJGD publishes articles on all disciplines of dentistry including the cariology, orthodontics, oral surgery, preventive dentistry, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research.Moreover, EJGD also publish the scientific researches evaluating the use of new biomaterials, new drugs and new methods for treatment of patients with different kinds of oral and maxillofacial diseases or defects, the diagnosis of oral and maxillofacial diseases with new methods, etc. Moreover, researches on the quality of life, psychological interventions, improving disease treatment outcomes, the prevention, diagnosis and management of cancer therapeutic complications, rehabilitation, palliative and end of life care, and support teamwork for cancer care and oral health care for old patients are also welcome. EJGD publishes research articles, case reports, reviews and comparison studies evaluating materials and methods in the all fields of related to dentistry.