Características operativas de técnicas moleculares empleadas para la detección del virus del papiloma humano en el proyecto ESTAMPA

IF 0.2 Q4 ONCOLOGY

Revista Colombiana de Cancerologia Pub Date : 2020-09-23 DOI:10.35509/01239015.106

Johana Andrea Lineros-Hurtado, Pilar Romero-Romero, Yuly Milena Salgado-Lerma, Carolina Wiesner-Ceballos

引用次数: 0

Abstract

The development and innovation of new technologies has improved the detection of high-risk human papillomavirus infection. Hybrid capture II is an assay that is based on hybridization and chemiluminescence. Cobas HPV Test is a qualitative PCR and Aptima HPV Assay allows to detect the expression of messenger RNA of the high-risk HPV E6 / E7 oncoproteins. These techniques have advantages, in comparison, with conventional cytology that is routinely used for the detection of cervical cancer. In the ESTAMPA study, 13,691 prosecutions were carried out that allowed to identify that for the planning of research projects or for the implementation of HPV screening tests, it is necessary to analyze the advantages and disadvantages of market tests.

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ESTAMPA项目中用于检测人类乳头瘤病毒的分子技术的操作特点

新技术的发展和创新提高了对高危人乳头瘤病毒感染的检测。杂交捕获II是一种基于杂交和化学发光的测定方法。Cobas HPV检测是一种定性PCR，Aptima HPV检测可以检测高危HPV E6/E7癌蛋白的信使RNA的表达。与常规用于检测宫颈癌症的传统细胞学相比，这些技术具有优势。在ESTAMPA的研究中，进行了13691次起诉，以确定为了规划研究项目或实施HPV筛查测试，有必要分析市场测试的优缺点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Colombiana de Cancerologia ONCOLOGY-

自引率

50.00%

发文量

期刊介绍： The Revista Colombiana de Cancerología is an official publication of the Instituto Nacional de Colombia (INC). The Revista is published quarterly with the aim of broadening and disseminating knowledge in the field of oncology. The Revista publishes articles on: molecular carcinogenic mechanisms and treatment responses; cancer epidemiology; clinical features and treatment of neoplastic disease and public health campaigns to control cancer. Manuscripts which contain original material shall be accepted for possible publication. Neither the article nor any part of its contents (including statistical or graphic content) may have been published or submitted for publication in any media other than the Revista Colombiana de Cancerología. No acceptance shall be made of preliminary reports (abstracts or posters) presented at scientific meetings, neither of press releases on programmed meetings. All manuscript copies shall be placed at the disposition of the Journal Editorial Board. Under exceptional circumstances, secondary publications in Spanish or other languages may be submitted, provided they comply with certain conditions which justify said submission.