Long-term results of Boston keratoprosthesis surgery in Polish patients

IF 0.2 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
A. Nowinska, D. Dobrowolski, E. Wróblewska-Czajka, U. Jurkunas, E. Wylęgała
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Abstract

Abstract Introduction To evaluate the long-term (10 year) outcomes of Boston type 1 keratoprosthesis (BKPro; Massachusetts Eye and Ear Infirmary, Boston, MA) surgery performed in 6 Polish patients. Materials and Methods 6 eyes of 6 patients (1 female and 5 males; mean age 49,5±6,34 years) were qualified for the surgery. Indications for BKPro surgery in the study group included: corneal graft failure (3 patients), chemical ocular burns (2 patients), and post-herpetic keratitis vascularized leucoma (1 patient). Visual acuity, slit-lamp examination with ocular surface assessment, anterior segment optical coherence tomography (AS OCT), fundoscopy, and intraocular digital pressure measurement were performed at each visit. Results Retention of keratoprosthesis was achieved in all patients during the follow-up period. At last recorded visits VA≥0,2 was observed in 3 patients, LP in one patient and NLP in 2 patients. The complications which occurred in our case series were: glaucoma (4 patients preoperatively, 6 patients postoperatively), retroprosthetic membrane formation (1 patient), epimacular membrane formation (2 patients) and severe Meibomian Gland Dysfunction (3 patients). OCT analysis allowed imaging of anterior iris synechiae, AGV tube, protrusion of the BKPro and retroprosthetic membrane not visible on the slit lamp examination. Conclusions BKPro surgery should be considered as a surgery of choice in patients who have high risk of PK failure. OCT plays a role in anterior eye segment monitoring and detection of complications not visible on the slit lamp examination in the follow up period. Implementing the dry eye disease treatment should be recommended in all patients undergoing BKPro surgery.
波兰患者波士顿角膜假体手术的长期效果
摘要:评价波士顿1型角膜假体(BKPro;马萨诸塞州眼耳医院(Massachusetts Eye and Ear Infirmary, Boston, MA)对6名波兰患者进行手术。材料与方法6例患者6眼(女1例,男5例;平均年龄(49,5±6,34岁)符合手术条件。研究组BKPro手术的适应症包括:角膜移植失败(3例)、眼部化学烧伤(2例)、疱疹后角膜炎血管性白斑(1例)。每次就诊时进行视力、裂隙灯检查及眼表评估、前段光学相干断层扫描(AS OCT)、眼底镜检查和眼内数字压测量。结果所有患者在随访期间均获得角膜假体保留。最后记录就诊次数VA≥0,2例,LP 1例,NLP 2例。本组病例发生的并发症有:青光眼(术前4例,术后6例)、假体后膜形成(1例)、黄斑外膜形成(2例)、重度睑板腺功能障碍(3例)。OCT分析显示前虹膜粘连、AGV管、BKPro突出和假体后膜在裂隙灯检查中未见。结论对于PK衰竭高危患者,应考虑行BKPro手术。在随访期间,OCT在前眼段监测和发现裂隙灯检查未见的并发症方面发挥了重要作用。所有接受BKPro手术的患者都应推荐实施干眼病治疗。
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来源期刊
Postȩpy higieny i medycyny doświadczalnej
Postȩpy higieny i medycyny doświadczalnej MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
0.60
自引率
0.00%
发文量
50
审稿时长
4-8 weeks
期刊介绍: Advances in Hygiene and Experimental Medicine (PHMD) is a scientific journal affiliated with the Institute of Immunology and Experimental Therapy by the Polish Academy of Sciences in Wrocław. The journal publishes articles from the field of experimental medicine and related sciences, with particular emphasis on immunology, oncology, cell biology, microbiology, and genetics. The journal publishes review and original works both in Polish and English. All journal publications are available via the Open Access formula in line with the principles of the Creative Commons licence.
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