Boundary Layer Effects on Ionic Flows Via Classical Poisson-Nernst-Planck Systems

Q2 Mathematics
Mingji Zhang
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引用次数: 16

Abstract

Abstract A quasi-one-dimensional steady-state Poisson-Nernst-Planck model of two oppositely charged ion species through a membrane channel is analyzed. The model problem is treated as a boundary value problem of a singularly perturbed differential system. Our analysis is based on the geometric singular perturbation theory but, most importantly, on specific structures of this concrete model. The existence and (local ) uniqueness of solutions to the boundary value problem is established. In particular, an approximation of both the individual flux and the I-V (current-voltage) relation are derived explicitly from the zeroth order approximation (in ") solutions, from which the boundary layer effects on ionic flows are studied in great details.
经典泊松-能-普朗克系统中离子流动的边界层效应
摘要分析了两种带相反电荷的离子通过膜通道的准一维稳态Poisson-Nernst-Planck模型。将模型问题视为奇摄动微分系统的边值问题。我们的分析基于几何奇异摄动理论,但最重要的是,基于该具体模型的特定结构。建立了边值问题解的存在性和(局部)唯一性。特别是,从零阶近似(In”)解中明确推导出了单个通量和I-V(电流-电压)关系的近似值,从中详细研究了边界层对离子流的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Computational and Mathematical Biophysics
Computational and Mathematical Biophysics Mathematics-Mathematical Physics
CiteScore
2.50
自引率
0.00%
发文量
8
审稿时长
30 weeks
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