Response to the Letter: Mean Platelet Volume and Related Parameters May Not Contribute to the Diagnosis in Patients with Ascending Thoracic Aortic Aneurysm

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Y. Tekin, G. Tekin, İ. Korkmaz, Sefa Yurtbay
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引用次数: 0

Abstract

We carefully read the comments of dear colleagues Cengiz Beyan and Esin Beyan[1]. about our article titled “Mean Platelet Volume and Related Parameters May not Contribute to the Diagnosis in Patients with Ascending Thoracic Aortic Aneurysm”[2]. Beyan et al.[1] commented that “The control group did not consist of healthy volunteers, and it was made up of individuals who applied in the hospital at the same time. The fact that the control group is not composed of healthy volunteers and does not represent the society makes it difficult to interpret the results obtained.”. Our study results have a statistically significant value, and while we have excluded the patients previously diagnosed with hematological malignancy, chronic obstructive pulmonary disease (or COPD), autoimmune liver disease, cirrhosis, metastatic bone marrow infiltration, acute or chronic inflammatory disease — such as physical trauma, tonsillitis, asthma, rheumatoid arthritis, and active hepatitis —, and current or recent treatment (in the past three months) with oral or intravenous steroids or other medications that might cause pancytopenia from the control group according to their background, it is possible that all the exclusion criteria cannot be made in a retrospective study and that there can be pre-analytical and analytical errors, but this does not change the statistical difference. Additionally, Beyan et al.[1] tried to draw attention that mean platelet volume (MPV) is a complete blood count parameter whose measurement has not been standardized to date and, therefore, it has been reported to have no role in diagnosis and prognosis of acquired diseases according to a study, but there are many studies about the prognostic value of MPV in many clinical diseases. Vardon-Bounes et al.[3] reported that MPV was an independent predictive factor of 90-day mortality. They suggested that continuous monitoring of MPV may be a useful parameter to stratify mortality risk in septic shock. Ma et al.[4] reported that high MPV can be considered as an independent biomarker for predicting three-month mortality in patients with hepatitis B virus-related decompensated cirrhosis. Lee Response to the Letter: Mean Platelet Volume and Related Parameters May Not Contribute to the Diagnosis in Patients with Ascending Thoracic Aortic Aneurysm
对信函的回应:平均血小板体积和相关参数可能对胸升主动脉瘤患者的诊断没有帮助
我们仔细阅读了亲爱的同事Cengiz Beyan和Esin Beyan b[1]的评论。关于我们的文章《平均血小板体积和相关参数可能无助于胸升主动脉瘤患者的诊断》[2]。Beyan等人评论说:“对照组不是由健康的志愿者组成,而是由同时在医院申请的个人组成。”事实上,对照组不是由健康的志愿者组成的,也不代表社会,因此很难解释所获得的结果。我们的研究结果具有统计学意义,同时我们排除了既往诊断为血液恶性肿瘤、慢性阻塞性肺疾病(或COPD)、自身免疫性肝病、肝硬化、转移性骨髓浸润、急慢性炎症性疾病-的患者如身体创伤、扁桃体炎、哮喘、类风湿关节炎和活动性肝炎,以及目前或最近(过去三个月)口服或静脉注射类固醇或其他药物治疗可能导致对照组全血细胞减少症,根据其背景,可能无法在回顾性研究中制定所有排除标准,并且可能存在分析前和分析错误,但这不会改变统计差异。此外,Beyan等人([1])试图提请注意,平均血小板体积(mean platelet volume, MPV)是一个全血细胞计数参数,其测量方法迄今尚未标准化,因此有研究报道其在获得性疾病的诊断和预后中没有作用,但关于MPV在许多临床疾病中的预后价值的研究很多。Vardon-Bounes等人报道MPV是90天死亡率的独立预测因素。他们认为,持续监测MPV可能是对脓毒性休克死亡风险进行分层的有用参数。Ma等人报道,高MPV可被视为预测乙型肝炎病毒相关失代偿性肝硬化患者三个月死亡率的独立生物标志物。对信函的回应:平均血小板体积和相关参数可能对胸升主动脉瘤患者的诊断没有帮助
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来源期刊
Revista Brasileira De Cirurgia Cardiovascular
Revista Brasileira De Cirurgia Cardiovascular CARDIAC & CARDIOVASCULAR SYSTEMS-SURGERY
CiteScore
2.10
自引率
0.00%
发文量
176
审稿时长
20 weeks
期刊介绍: Brazilian Journal of Cardiovascular Surgery (BJCVS) is the official journal of the Brazilian Society of Cardiovascular Surgery (SBCCV). BJCVS is a bimonthly, peer-reviewed scientific journal, with regular circulation since 1986. BJCVS aims to record the scientific and innovation production in cardiovascular surgery and promote study, improvement and professional updating in the specialty. It has significant impact on cardiovascular surgery practice and related areas.
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