Cognitive Impairment Secondary to Treatment of Cured Brain Metastases of Triple-Negative Breast Carcinoma

Abstract

Materials and methods: We report the case of a 58 years old women cured of brain metastases from TNBC. Initial diagnosis was of locally advanced inflammatory TNBC for which the patient underwent high-dose neo-adjuvant chemotherapy followed by surgery, radiotherapy and adjuvant chemotherapy. Symptomatic brain metastases were diagnosed 10 months after the end of adjuvant chemotherapy. Whole-brain radiotherapy and stereotactic radiosurgery were rapidly delivered followed by twelve months of chemotherapy.